Results 41 to 50 of about 3,807 (135)

Structural Enzymology of Cellvibrio japonicus Agd31B Protein Reveals α-Transglucosylase Activity in Glycoside Hydrolase Family 31 [PDF]

, 2012
The metabolism of the storage polysaccharides glycogen and starch is of vital importance to organisms from all domains of life. In bacteria, utilization of these -glucans requires the concerted action of a variety of enzymes, including glycoside ...
Adams, Atsushi Izumi, Ball, Barends, Becker, Berezina, Boos, Burlingham, Cantarel, Cowtan, Davies, Davies, DeBoy, Dippel, Elbein, Emsley, Ernst, Gasteiger, Gibson, Gideon J. Davies, Glyn R. Hemsworth, Harry Brumer, Hazlewood, Hendlich, Humphry, Janecek, Johan Larsbrink, Jones, Jung, Kato, Kim, Kim, Kim, Larsbrink, Lee, Lee, Leemhuis, Leslie, Liebl, Lovering, Meissner, Mukai, Okuyama, Palmer, Perrakis, Przylas, Ren, Roach, Rossi, Roujeinikova, Roujeinikova, Schwartz, Seo, Sim, Sim, Sinnott, Stam, Stick, Sundqvist, Suzuki, Takaha, Takaha, Tan, Terada, Vagin, Vonrhein, Wang, Wilson, Winn, Withers, Yamamoto, Zhou   +71 more
core   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

From Stress to Success: Strategies for Improving Heat Tolerance in Wheat

Journal of Agronomy and Crop Science, Volume 211, Issue 3, May 2025.
ABSTRACT Wheat, a major staple crop, is critical for global food security. However, abiotic stresses, particularly heat stress, threaten crop productivity. With climate change predicted to increase temperatures by around 1.5°C by 2050, crop productivity could be severely affected.
Muhammad Ahmad, Maryium Sajjad, Aman Ullah, Usman Zulfiqar, Sami Ul‐Allah, Ejaz Ahmad Waraich, Kaleem ul Din, Kadambot H. M. Siddique, Muhammad Farooq   +8 more
wiley   +1 more source

mRNA therapy: A new frontier in regenerative medicine

Interdisciplinary Medicine, Volume 3, Issue 2, March 2025.
This review discussed the potential of mRNA drugs in regenearative medicine, highlighting the key processes of mRNA therapy, focusing on therapeutic mRNA modification and delivery carriers. The preclinical and clinical studies of mRNA therapeutics for regeneration of cardiac, lung, liver, kidney, locomotor system, skin lesions and neurological ...
Ding‐Ding Xue, Yue Zhang, An‐Ran Shen, Tao‐Tao Tang, Bi‐Cheng Liu, Lin‐Li Lv   +5 more
wiley   +1 more source

Lactate: brain fuel in human traumatic brain injury: a comparison with normal healthy control subjects. [PDF]

, 2015
We evaluated the hypothesis that lactate shuttling helps support the nutritive needs of injured brains. To that end, we utilized dual isotope tracer [6,6-(2)H2]glucose, that is, D2-glucose, and [3-(13)C]lactate techniques involving arm vein tracer ...
Brooks, George A, Glenn, Thomas C, Horning, Michael A, Hovda, David A, Martin, Neil A, McArthur, David L, Vespa, Paul   +6 more
core   +1 more source

Heterozygous GAA knockout is nonconsequential on metabolism and the spatial liver transcriptome in high‐fat diet‐induced obese and prediabetic mice

Physiological Reports, Volume 13, Issue 6, March 2025.
Abstract Glycophagy is the autophagic degradation of glycogen by the enzyme acid alpha‐glucosidase (GAA). Although GAA inhibitors improve metabolic health by inhibiting GAA in the intestine, it is not clear if GAA inhibition in peripheral tissues such as the liver is metabolically beneficial. This study tested if the heterozygous knockout of GAA (HetKO‐
Cameron P. McCall, Melina C. Mancini, Jaroslaw Staszkiewicz, Douglas G. Mashek, Timothy D. Heden   +4 more
wiley   +1 more source

Label-free and redox proteomic analyses of the triacylglycerol-accumulating Rhodococcus jostii RHA1 [PDF]

, 2015
The bacterium Rhodococcus jostii RHA1 synthesizes large amounts of triacylglycerols (TAG) under conditions of nitrogen starvation. To better understand the molecular mechanisms behind this process, we performed proteomic studies in this oleaginous ...
Alvarez, Hector Manuel, Dávila Costa, José Sebastián, Herrero, O. Marisa, Leichert, Lars   +3 more
core   +2 more sources

Characterization of starch debranching enzymes of maize endosperm [PDF]

, 1998
The goal of this research is to understand the biochemical lesion of the sugary1 mutation in maize. The sugary1 gene is a determinant of starch structure.
Rahman, Afroza
core   +2 more sources

Deubiquitinases as novel therapeutic targets for diseases

MedComm, Volume 5, Issue 12, December 2024.
Deubiquitinating enzymes (DUBs) are crucial for cellular homeostasis, modulating ubiquitination by removing ubiquitin or cleaving ubiquitin chains. With about 100 types in humans, DUBs balance the activity of E3 ubiquitin ligases, ensuring proteostasis and responses to stress.
Yali Xian, Jing Ye, Yu Tang, Nan Zhang, Cheng Peng, Wei Huang, Gu He   +6 more
wiley   +1 more source

Factors influencing glycogen branching enzyme activity in mouse liver [PDF]

, 2013
Glycogen is the storage polysaccharide in a spectrum of organisms ranging from yeast to humans. Glycogen has a highly branched structure somewhat resembling a tree or shrub, with the branch points formed by glucose molecules being joined by α 1,6 ...
Fuller, Scott
core   +2 more sources