Results 111 to 120 of about 42,767 (197)

Emerging therapy strategies for energy metabolism in acute myocardial infarction. [PDF]

open access: yesJ Transl Med
Ma R   +7 more
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

[Clinical analysis and follow-up outcomes of 25 pediatric cases with hepatic glycogen storage disease]. [PDF]

open access: yesZhonghua Gan Zang Bing Za Zhi
Liu WW   +5 more
europepmc   +1 more source

Diagnostic and therapeutic strategies for non-alcoholic fatty liver disease. [PDF]

open access: yesFront Pharmacol, 2022
Fu Y   +11 more
europepmc   +1 more source

A Cross‐Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker

open access: yesGlia, Volume 74, Issue 6, June 2026.
Distinct microglial subpopulations are depicted, highlighting variations in gene expression and functional roles in response to specific disease conditions and the complexity of microglial activation and differentiation in neurodegeneration. ABSTRACT Microglial cells are key players in maintaining brain homeostasis and responding to pathological ...
Alessandro Palma   +6 more
wiley   +1 more source

Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Integrated secretome and phosphoprotein profiling of human nucleus pulposus cells revealed that IL‐1β and TLR2/6 activation induce a shared degenerative program, defined by consistent upregulation of IL‐6, IL‐8, GRO‐α, ICAM‐1, and MMP‐7 and convergence on NF‐κB/AP‐1 signaling.
Exarchos Kanelis   +4 more
wiley   +1 more source

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review). [PDF]

open access: yesInt J Mol Med
Liang Y   +12 more
europepmc   +1 more source

Metabolic Health and Fitness Do Not Differ Substantially Between Overweight Adults With and Without α‐Actinin‐3 Deficiency

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Untrained overweight α‐actinin‐3‐deficient (XX; 20 men, 19 women) and α‐actinin‐3‐expressing (RR; 20 men, 21 women) participants were included in the study. No major differences were observed between the XX and RR groups for metabolic health markers, anthropometrical and body composition features, cardiopulmonary capacity, and muscle strength. Notably,
Tomas Venckunas   +13 more
wiley   +1 more source

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