Results 251 to 260 of about 67,076 (344)

Carbohydrate intake of 10 g/kg body mass rapidly replenishes liver, but not muscle glycogen contents, during 12 h of post‐exercise recovery in well‐trained cyclists

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Exhaustive cycling exercise substantially reduces liver and muscle glycogen stores. During 12 h of post‐exercise recovery without carbohydrate intake, glycogen stores remain depleted. In contrast, when carbohydrate is consumed at 10 g/kg body mass (BM), provided during the first 6 h as sucrose beverages (1.2 g/kg BM/h), liver ...
Cas J. Fuchs   +15 more
wiley   +1 more source

Multi‐omic data integration and exploiting metabolic models using systems biology approach increase precision in subtyping and early diagnosis of cancer

open access: yesQuantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cancer is a complex and heterogeneous disease characterized by various genetic and epigenetic alterations. Early diagnosis, accurate subtyping, and staging are essential for effective, personalized treatment and improved survival rates. Traditional diagnostic methods, such as biopsies, are invasive and carry operational risks that hinder ...
Ezgi Tanıl, Emrah Nikerel
wiley   +1 more source

Integral kidney function assessment in pediatric patients with glycogen storage diseases. [PDF]

open access: yesFront Pediatr
Reyes-Apodaca M   +4 more
europepmc   +1 more source

Enzyme response to thyrotoxicosis and hypothyroidism in human liver and muscle [PDF]

open access: yes, 1972
Bachmaier, B.   +5 more
core  

Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection

open access: yesGlia, Volume 73, Issue 10, Page 2003-2024, October 2025.
Main Points Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa   +7 more
wiley   +1 more source

Molecular architecture and catalytic mechanism of human glycogen debranching enzyme. [PDF]

open access: yesNat Commun
Guan H   +7 more
europepmc   +1 more source

Pediatric liver transplantation with cyclosporine and steroids [PDF]

open access: yes, 1984
Gartner, JC   +6 more
core  

Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts

open access: yesInternational Journal of Cancer, Volume 157, Issue 7, Page 1304-1315, 1 October 2025.
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang   +7 more
wiley   +1 more source

Updated Gene Therapy for Renal Inborn Errors of Metabolism. [PDF]

open access: yesGenes (Basel)
Hergenrother S   +4 more
europepmc   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

open access: yesAnnals of Neurology, Volume 98, Issue 3, Page 448-470, September 2025.
[Color figure can be viewed at www.annalsofneurology.org] Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical ...
Brent L. Fogel   +10 more
wiley   +1 more source

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