Results 141 to 150 of about 448,615 (401)
Journal of Functional Foods, 2012 Tumour necrosis factor-α (TNF-α) plays a pivotal role in cellular insulin resistance and can induce insulin resistance in mouse FL83B hepatocytes. Caffeic acid and cinnamic acid were found to improve glucose uptake in TNF-α-treated insulin-resistant ...
Da-Wei Huang, Szu-Chuan Shen
doaj
Monitoring subunit rotation in single FRET-labeled FoF1-ATP synthase in an anti-Brownian electrokinetic trap [PDF]
, 2013 FoF1-ATP synthase is the membrane protein catalyzing the synthesis of the 'biological energy currency' adenosine triphosphate (ATP). The enzyme uses internal subunit rotation for the mechanochemical conversion of a proton motive force to the chemical bond.
arxiv +1 more source
Dynamic Akt/mTOR Signaling in Children with Autism Spectrum Disorder. [PDF]
, 2017 Autism spectrum disorder (ASD) is a behaviorally defined disorder affecting 1 in 68 children. Currently, there is no known cause for the majority of ASD cases nor are there physiological diagnostic tools or biomarkers to aid behavioral diagnosis.
Ashwood, Paul +3 more
core +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
36 degree step size of proton-driven c-ring rotation in FoF1-ATP synthase [PDF]
arXiv, 2009 Synthesis of the biological "energy currency molecule" adenosine triphosphate ATP is accomplished by FoF1-ATP synthase. In the plasma membrane of Escherichia coli, proton-driven rotation of a ring of 10 c subunits in the Fo motor powers catalysis in the F1 motor. While F1 uses 120 degree stepping, Fo models predict a step-by-step rotation of c subunits
arxiv
Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes
Epilepsia Open, EarlyView.Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola +3 more
wiley +1 more source
Exploration, EarlyView.Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang +4 more
wiley +1 more source
Sediment pollutant exposures caused hepatotoxicity and disturbed glycogenesis
Ecotoxicology and Environmental Safety, 2023 Liver metabolic syndrome, which involves impaired hepatic glycogen synthesis, is persistently increased by exposure to environmental pollutants. Most studies have investigated the pathogenesis of liver damage caused by single metal species or pure ...
Meng-Wei Lin +11 more
doaj
Asymmetry of rotational catalysis of single membrane-bound F0F1-ATP synthase [PDF]
arXiv, 2007 Erroneous submission in violation of copyright removed by arXiv admin.
arxiv
Journal of Psychiatry & Neuroscience, 2012 Mental illnesses, such as bipolar disorder, attention-deficit/hyperactivity disorder, depression and schizophrenia are a major public health concern worldwide. Several pharmacologic agents acting on monoamine neurotransmission are used for the management
J. Beaulieu
semanticscholar +1 more source