Results 251 to 260 of about 448,615 (401)

The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat

open access: yesExperimental Physiology, EarlyView.
Abstract The mood stabilizers lithium and valproate are psychotropic medications widely used in clinical practice. Despite their proven benefits, many individuals stop their treatment due to the adverse effects. Chronic diarrhoea is a common reason for discontinuation of these drugs; however, the underlying mechanisms are unknown.
Sofia Cussotto   +10 more
wiley   +1 more source

Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments.

open access: yesPharmacology and Therapeutics, 2014
M. K. King   +5 more
semanticscholar   +1 more source

Elevated cortisol concentration in preterm sheep fetuses impacts heart development

open access: yesExperimental Physiology, EarlyView.
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi   +9 more
wiley   +1 more source

Biogenesis and reformation of synaptic vesicles

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Synaptic vesicle proteins are axonally transported in precursor vesicles (PVs) before conversion into mature synaptic vesicles (SVs) that are reformed by local recycling at synapses. Abstract Communication within the nervous system relies on the calcium‐triggered release of neurotransmitter molecules by exocytosis of synaptic ...
Svenja Bolz, Volker Haucke
wiley   +1 more source

In silico and in vitro Evaluation of the Cytotoxic Potential of Hinokitiol against Osteosarcoma by Targeting Glycogen Synthase Kinase 3β. [PDF]

open access: yesTurk J Pharm Sci
Cheriyan BV   +7 more
europepmc   +1 more source

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