Results 271 to 280 of about 149,215 (350)

18F‐Radiopharmaceutical Diversification Enabled by Deaminative Cross‐Electrophile Couplings

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
A general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Isabella F. Ogilvy, Joseph Ford, Sebastiano Ortalli, Evelien Renders, Thomas R. Hayes, Shuanglong Liu, Inne Mortiers, Anastasia Nikolopoulou, Alexandre M. Sorlin, Andrés A. Trabanco, Matthew Tredwell, Peter J. J. A. Buijnsters, Rhys Salter, Véronique Gouverneur   +13 more
wiley   +2 more sources

The Glycogen Synthase Kinase-3 Inhibitor CHIR99021 Reduces Fatty Infiltration and Muscle Atrophy After Rotator Cuff Tears: An In Vitro Experiment and In Vivo Mouse Model. [PDF]

Am J Sports Med
Zhang P, Zhou M, Zhu Y, Xie J, Huo Z, Zhang D, Li P, Guo J, Li G, Li X, Wang R, Jiang C.   +11 more
europepmc   +1 more source

Back to the Fungimentals: Antimycotic Activity of Glycogen Synthase Kinase

American Medical Association 2025, Lach, Nathan   +1 more
openalex   +1 more source

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Radiosynthesis and evaluation of a novel ¹⁸F-labeled tracer for PET imaging of glycogen synthase kinase 3. [PDF]

Am J Nucl Med Mol Imaging
Xiao Z, Li Y, Haider A, Pfister SK, Rong J, Chen J, Zhao C, Zhou X, Song Z, Gao Y, Patel JS, Collier TL, Ran C, Zhai C, Yuan H, Liang SH.   +15 more
europepmc   +1 more source

Persimmon carotenoid extract rich in β‐cryptoxanthin improves glucose homeostasis and reduces liver damage in high‐fat‐diet‐induced type 2 diabetic and metabolic dysfunction‐associated steatotic liver disease mice

Journal of the Science of Food and Agriculture, Volume 106, Issue 2, Page 1299-1313, 30 January 2026.
Abstract Background Persimmon (Diospyros kaki Thunb.) byproducts are a remarkable source of bioactive compounds, particularly carotenoids. Several studies suggest that carotenoids have beneficial effects in prevention of a large number of diseases. This study aims to highlight the effects of a persimmon carotenoid extract (PSCE) rich in β‐cryptoxanthin
Bryan Moreno‐Chamba, Nuria Martí, Antonio Cárdenas, María Soledad Fernández‐Pachón, Blanca Escudero‐López, Franz Martín, Julio Salazar‐Bermeo, Manuel Valero, Domingo Saura, María Concepción Martínez‐Madrid, Genoveva Berná   +10 more
wiley   +1 more source

Glycogen synthase kinase 3 activity enhances liver inflammation in MASH. [PDF]

JHEP Rep
Khoury M, Guo Q, Furuta K, Correia C, Meroueh C, Kim Lee HS, Warasnhe K, Valenzuela-Pérez L, Mazar AP, Kim I, Noh YK, Holmes H, Romero MF, Sussman CR, Pavelko KD, Islam S, Bamidele AO, Hirsova P, Li H, Ibrahim SH.   +19 more
europepmc   +1 more source

Correction: Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element. [PDF]

BMC Mol Cell Biol
Finlay D, Patel S, Dickson LM, Shpiro N, Marquez R, Rhodes CJ, Sutherland C.   +6 more
europepmc   +1 more source

Glycogen synthase kinase 3 signaling in neural regeneration in vivo. [PDF]

J Mol Cell Biol
Zhang J, Yang SG, Zhou FQ.
europepmc   +1 more source

BF2 Complexes of N‐arylated 1‐amino‐anthraquinone, ‐xanthone, ‐thioxanthone, and Related Compounds: Synthesis and Properties

European Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.
Syntheses of BF2 complexes of 1‐(arylamino)anthraquinones and related compounds are developed and their properties studied. The physical properties of anthraquinones can be modulated by the introduction of arylamino groups next to the carbonyl function.
Ahlem N. Khelf‐Maghraoui, Ghenia Bentabed‐Ababsa, Nicolas Mast, William Erb, Jean‐Pierre Hurvois, Thierry J. Roisnel, Nicolas Richy, Guillaume Calvez, Olivier Mongin, Charline Piroud, Thomas Robert, Stéphane Bach, Florence Mongin   +12 more
wiley   +1 more source