Results 321 to 330 of about 454,859 (358)
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1986
Publisher Summary This chapter reviews knowledge of mammalian liver glycogen synthase and its short-term regulation by covalent phosphorylation mechanisms. Elevated concentrations of insulin and glucose promote glycogen synthesis and the activation of glycogen synthase.
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Publisher Summary This chapter reviews knowledge of mammalian liver glycogen synthase and its short-term regulation by covalent phosphorylation mechanisms. Elevated concentrations of insulin and glucose promote glycogen synthesis and the activation of glycogen synthase.
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Glycogen synthase in prenatal rat liver
Biochemical and Biophysical Research Communications, 1985Glycogen synthase first appears in significant levels in fetal rat liver on day 18 of gestation (22 day term), but in a mostly inactive, phospho- form. This was reflected in a decreased affinity for its allosteric activator (increased A0.5 for glucose-6-phosphate), and with limited glycogen synthesis and accumulation.
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Structure and Regulation of Glycogen Synthase in the Brain
2019Brain glycogen synthesis is a regulated, multi-step process that begins with glucose transport across the blood brain barrier and culminates with the actions of glycogen synthase and the glycogen branching enzyme to elongate glucose chains and introduce branch points in a growing glycogen molecule.
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Glycogen Synthase Kinase 3: A Kinase for All Pathways?
Current Topics in Developmental Biology, 2017P. Patel, J. Woodgett
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New insights into activation and function of the AMPK
Nature Reviews Molecular Cell Biology, 2023Grahame Hardie
exaly
Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease.
European journal of medicinal chemistry, 2016Mudasir Maqbool +2 more
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Natural and synthetic bioactive inhibitors of glycogen synthase kinase.
European journal of medicinal chemistry, 2017Imran A Khan +3 more
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1986
Publisher Summary This chapter discusses the structure and activity of muscle glycogen synthase. Glycogen synthase is regulated by a phosphorylation–dephosphorylation mechanism. Following the discovery that glycogen phosphorylase and phosphorylase kinase were activated by phosphorylation, Larner and co-workers found that glycogen synthase could exist
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Publisher Summary This chapter discusses the structure and activity of muscle glycogen synthase. Glycogen synthase is regulated by a phosphorylation–dephosphorylation mechanism. Following the discovery that glycogen phosphorylase and phosphorylase kinase were activated by phosphorylation, Larner and co-workers found that glycogen synthase could exist
openaire +2 more sources