Results 81 to 90 of about 2,746 (210)

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Bioactive PLGA polymer nanoparticle loaded gels for atopic dermatitis treatment

Discover Applied Sciences
Atopic dermatitis (AD) is a major chronic inflammatory skin disease that causes itching, redness and irritation. Categorized as the largest skin disability, it poses a substantial financial and social burden on patients.
Eun Ju Park, Belle Lin Hwee Yap, Xinning Wang, Qi Zhen Poh, Chee Hian Tan, Li Fang Koh, John E. Common, Peili Teo   +7 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

The efficacy of topical treatments for acanthosis nigricans: a systematic review of randomized controlled trials

Frontiers in Medicine
BackgroundAcanthosis nigricans (AN) is a skin disorder marked by darkening and thickening of the skin, often linked to metabolic abnormalities. This systematic review of randomized controlled trials (RCTs) assesses the comparative effectiveness and ...
Awadh Alamri, Awadh Alamri, Awadh Alamri, Rose A. Alraddadi, Rose A. Alraddadi, Dhaii Alzahrani, Dhaii Alzahrani, Amal H. Abualola, Hadeel A. Maaddawi, Renad F. Alharthy, Renad F. Alharthy, Alanoud Y. Alkhashan, Maria Y. Ashqan, Esraa A. Shaheen, Bashaer Almahdi, Hatoon M. Althobaiti   +15 more
doaj   +1 more source

Dual‐targeted nanomedicine delivering doxorubicin and nitric oxide for tumor immunomodulation and synergistic therapy

BMEMat, EarlyView.
The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng, Wei Chen, Shuyu Li, Xiaomin Ma, Yanfeng Dai, Yan Wang, Changqiang Xie, Yazhe Xiao, Hesong Han, Yumiao Zhang, Junjie Wang   +10 more
wiley   +1 more source

Experimental methods in chemical engineering: Cyclic voltammetry—CV

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Cyclic voltammetry (CV) is a foundational electroanalytical technique for investigating redox behaviour and evaluating material performance across fields such as molecular electrochemistry, electrocatalysis, sensing, and energy storage. Despite its widespread use, a gap remains between formal electrochemical theory and the practical data ...
Yasser Matos‐Peralta, Christopher Panaritis, JoElen Hagler, Clara Santato, Gregory S. Patience   +4 more
wiley   +1 more source

Synergistic Catalysis for Closed‐Loop Alcohol Refining: Concurrent H2 Evolution and Selective Oxidation

EcoEnergy, EarlyView.
Photocatalytic, electrocatalytic, and photoelectrocatalytic systems exhibit a clear synergistic integration logic in closed‐loop alcohol refining—concurrently driving hydrogen evolution and selective alcohol oxidation to enable the directed conversion of alcohols into high‐value chemicals.
Wei Ren, Jinhe Li, Banghu Wei, Mohamed Hussein Abdurahman, Ahmad Zuhairi Abdullah, Xiaohui Yu, Weikang Wang, Qinqin Liu   +7 more
wiley   +1 more source

ZnO Nanowires by Chemical Bath Deposition: A Review on Doping and Functional Devices

Electron, EarlyView.
This review reports the most recent and well‐established state‐of‐the‐art and scientific challenges related to the doping of ZnO nanowires by chemical bath deposition, encompassing native point and hydrogen‐related defects, as well as extrinsic dopants.
Clément Lausecker, Adrien Baillard, Estelle Appert, Vincent Consonni   +3 more
wiley   +1 more source