Competition driven cancer immunoediting [PDF]
arXiv, 2014 It is a well-established fact that tumors up-regulate glucose consumption to meet increasing demands for rapidly available energy by switching to purely glycolytic mode of glucose metabolism. What is often neglected is that cytotoxic cells of the immune system also have increased energy demands and also switch to pure glycolysis when they are in an ...
arxiv
An experimental enquiry upon glycolysis in drawn blood [PDF]
, 1902 F. W. Pavy, R. L. Siau
openalex +1 more source
P53 Orchestrates Cancer Metabolism: Unveiling Strategies to Reverse the Warburg Effect [PDF]
arXivCancer cells exhibit significant alterations in their metabolism, characterised by a reduction in oxidative phosphorylation (OXPHOS) and an increased reliance on glycolysis, even in the presence of oxygen. This metabolic shift, known as the Warburg effect, is pivotal in fuelling cancer's uncontrolled growth, invasion, and therapeutic resistance.
arxiv
Immune Evasion through Competitive Inhibition: the Shielding Effect of non-Stem Cancer Cells [PDF]
arXiv, 2014 It has been recently proposed that the two "emerging" hallmarks of cancer, namely altered glucose metabolism and immune evasion, may in fact be fundamentally linked (Kareva and Hahnfeldt, 2013). This connection comes from up-regulation of glycolysis by tumor cells, which can lead to active competition for resources in the tumor microenvironment between
arxiv
GLYCOLYSIS IN THE BLOOD OF PATIENTS WITH PERNICIOUS ANEMIA [PDF]
, 1933 S. M. Goldhamer
openalex +1 more source
Cell Death DiscoveryAlthough increased aerobic glycolysis is common in various cancers, pancreatic ductal adenocarcinoma (PDAC) cells can survive a state of glycolysis suppression. We aimed to identify potential therapeutic targets in glycolysis-suppressed PDAC cells.
Zhiheng Zhang +10 more
doaj +1 more source
Petri nets in modelling glucose regulating processes in the liver [PDF]
arXivDiabetes is a chronic condition, considered one of the civilization diseases, that is characterized by sustained high blood sugar levels. There is no doubt that more and more people is going to suffer from diabetes, hence it is crucial to understand better its biological foundations.
arxiv
Inferring biological networks by sparse identification of nonlinear dynamics [PDF]
arXiv, 2016 Inferring the structure and dynamics of network models is critical to understanding the functionality and control of complex systems, such as metabolic and regulatory biological networks. The increasing quality and quantity of experimental data enable statistical approaches based on information theory for model selection and goodness-of-fit metrics. We
arxiv
AN EXPERIMENTAL STUDY OF BLOOD GLYCOLYSIS. THE EFFECTS OF THYROID AND ADRENAL EXTRACTS AND PHLORHIZIN ON GLYCOLYSIS IN VITRO [PDF]
, 1915 G. M. Mackenzie
openalex +1 more source
The impact of glycolysis on ischemic stroke: from molecular mechanisms to clinical applications
Frontiers in NeurologyIschemic stroke (IS), a leading cause of disability and mortality worldwide, remains a significant challenge due to its complex pathogenesis. Glycolysis, a central metabolic pathway, plays a critical role in bridging the gap between metabolic dysfunction
Yingquan Liu +4 more
doaj +1 more source