Results 91 to 100 of about 291,093 (299)

Respiration and Glycolysis in Bovine Dental Pulp

, 1969
Successive manometric determinations of oxygen, aerobic carbon dioxide, and anaerobic carbon dioxide quotients for the same samples of bovine dental pulp indicated that glucose depresses the oxygen consumption rate and that respiration depresses the ...
Alton K. Fisher, Christian Schwabe
core   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Fe-containing magnetic ionic liquid as an effective catalyst for the glycolysis of poly(ethylene terephthalate)

, 2010
The depolymerization of poly(ethylene terephthalate) (PET) in ethylene glycol could be catalyzed by imidazolium-based Fe-containing ionic liquid, 1-butyl-3-methylimidazolium tetrachloroferrate ([bmim]FeCl(4)).
Zhang, Xiangping, Yan, Ruiyi, Li, ZX, Wang, Hui, Li, Zengxi, Zhang, Suojiang, Hui Wang, Ruiyi Yan, Zengxi Li, Suojiang Zhang, Xiangping Zhang   +10 more
core   +1 more source

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

Advanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi, Mingwei Wang, Duo Yu, Mingqi Zhao, Xinyan Wang, Shiqi Li, Xiaowen Han, Wei Wei, Shunzi Jin   +8 more
wiley   +1 more source

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation [PDF]

, 2011
Warburg's observation that cancer cells exhibit a high rate of glycolysis even in the presence of oxygen (aerobic glycolysis) sparked debate over the role of glycolysis in normal and cancer cells.
Matthew G. Vander Heiden, Lunt, Sophia Yunkyungkwon, Sophia Y. Lunt, Vander Heiden, Matthew G.   +3 more
core   +1 more source

AI‐Assisted Tumor Boundary Delineation via Targeted Ultrasmall Iron Oxide Nanoprobe for High‐Contrast HER2‐Positive Tumor Imaging

Advanced Science, EarlyView.
A novel targeted and pH‐responsive MRI contrast agent was integrated with a 3D nnU‐Net deep learning framework to enable accurate delineation of tumor boundary morphology in HER2‐positive breast cancer imaging. ABSTRACT Breast cancer continues to be a leading cause of cancer‐related mortality in women globally, where precise diagnosis and clear tumor ...
Jiaying Zheng, Yi Zhu, Xinrui Li, Sunxian Dai, Xiangyuan Ma, Hongwei Lu, Zhongling Wang, Benqing Zhou   +7 more
wiley   +1 more source

The activation of the metabolic oxaloacetate-pyruvate axis restores influenza A virus replication during impaired glycolysis

Virology Journal
Viruses strongly depend on the host cell for efficient replication and influenza A virus (IAV) amongst others also lead to remarkable changes of the host cell metabolism.
Chiara Robin Bojarzyn, Nadine Bieß, Matthias Behrens, Hans-Ulrich Humpf, Stephan Ludwig, Eike R. Hrincius   +5 more
doaj   +1 more source

TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemia

Journal of Hematology & Oncology, 2016
Background Cancer cells show increased glycolysis and take advantage of this metabolic pathway to generate ATP. The TP53-induced glycolysis and apoptosis regulator (TIGAR) inhibits aerobic glycolysis and protects tumor cells from intracellular reactive ...
Sixuan Qian, Jianyong Li, Ming Hong, Yu Zhu, Huihui Zhao, Yue Xie, Jiayu Huang, Yun Lian, Yanru Li, Shuai Wang, Jianping Mao, Yaoyu Chen   +11 more
doaj   +1 more source

Modeling of the Glycolysis Pathway in Plasmodium falciparum using Petri Nets [PDF]

, 2016
Malaria is one of the deadly diseases, which affects a large number of the world’s population. The Plasmodium falciparum parasite during erythrocyte stages produces its energy mainly through anaerobic glycolysis, with pyruvate being converted into ...
Rotimi, Solomon, Oyelade, O. J., Okunoren, Ifeoluwa, Ifeoluwa Okunoren, Isewon, Itunuoluwa, Itunuoluwa Isewon, Solomon Rotimi, Jelili Oyelade   +7 more
core  

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source