Results 71 to 80 of about 339,187 (240)

Glycolysis-related genes from the REACTOME_GLYCOLYSIS.

open access: yes, 2022
(DOCX)
Reeree Lee (13889369)   +8 more
core   +1 more source

Targeting Glycolysis in Alloreactive T Cells to Prevent Acute Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia Effect

open access: yesFrontiers in Immunology, 2022
Alloreactive donor T cells undergo extensive metabolic reprogramming to become activated and induce graft-versus-host disease (GVHD) upon alloantigen encounter.
Ying Huang   +27 more
doaj   +1 more source

Enhanced glycolysis is associated with aggressive tumor phenotype and worse outcomes in hepatocellular carcinoma patients

open access: yesFrontiers in Medicine
BackgroundAdenosine Triphosphate (ATP) is mainly generated by oxidative phosphorylation in non-malignant cells, whereas malignant cells rely predominantly on glycolysis for energy production, known as the “Warburg effect.” This study used the gene set ...
Masanori Oshi   +8 more
doaj   +1 more source

2-Deoxyglucose alleviates migraine-related behaviors by modulating microglial inflammatory factors in experimental model of migraine

open access: yesFrontiers in Neurology, 2023
BackgroundTargeting metabolic pathways has emerged as a new migraine treatment strategy as researchers realize the critical role metabolism plays in migraine. Activated inflammatory cells undergo metabolic reprogramming and rely on glycolysis to function.
Tao Qiu   +9 more
doaj   +1 more source

PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis

open access: yesScientific Reports, 2022
Heart failure (HF) is a global pandemic which affects about 26 million people. PFKM (Phosphofructokinase, Muscle), catalyzing the phosphorylation of fructose-6-phosphate, plays a very important role in cardiovascular diseases. However, the effect of PFKM
Min Zhou   +5 more
doaj   +1 more source

Glycolysis in the tumor microenvironment: a driver of cancer progression and a promising therapeutic target

open access: yesFrontiers in Cell and Developmental Biology
Even with sufficient oxygen, tumor cells use glycolysis to obtain the energy and macromolecules they require to multiply, once thought to be a characteristic of tumor cells known as the “Warburg effect”. In fact, throughout the process of carcinogenesis,
Junpeng Zhao   +11 more
semanticscholar   +1 more source

Enhanced glycolysis in granulosa cells promotes the activation of primordial follicles through mTOR signaling

open access: yesCell Death and Disease, 2022
In mammals, nonrenewable primordial follicles are activated in an orderly manner to maintain the longevity of reproductive life. Mammalian target of rapamycin (mTOR)-KIT ligand (KITL) signaling in pre-granulosa cells and phosphatidylinositol 3-kinase ...
Xiaodan Zhang   +10 more
semanticscholar   +1 more source

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology

open access: yes, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
Vazquez, Alexei   +8 more
core   +1 more source

Glycolysis of poly(ethylene terephthalate) catalyzed by ionic liquids

open access: yes, 2009
Poly(ethylene terephthalate) (PET) from an industrial manufacturer was depolymerized by ethylene glycol in the presence of a novel catalyst: ionic liquids.
Zhang, Yanqiang   +6 more
core   +1 more source

HPV E6/E7 promotes aerobic glycolysis in cervical cancer by regulating IGF2BP2 to stabilize m6A-MYC expression

open access: yesInternational Journal on Biological Sciences, 2022
Enhanced aerobic glycolysis constitutes an additional source of energy for tumor proliferation and metastasis. Human papillomavirus (HPV) infection is the main cause of cervical cancer (CC); however, the associated molecular mechanisms remain poorly ...
Chenchen Hu   +18 more
semanticscholar   +1 more source

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