Results 71 to 80 of about 291,093 (299)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

glycolysis and gluconeogenesis-html

, 2014
glycolysis and ...
Karen Fugate (480954)
core   +1 more source

A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes [PDF]

, 2013
peer reviewedWe present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a
Carroll, Kathleen M, Paton, Norman W, Mendes, Pedro, McCarthy, John E G, Carroll, K.M., Weichart, D., Broomhead, David S., Murabito, Ettore, Khan, Farid, Messiha, Hanan L.,, Dunn, Warwick B., Oliver, Stephen G,, Swainston, N., Broomhead, D. S., Dada, Joseph O., Oliver, Stephen G., Westerhoff, H.V.; id_orcid, Kell, Douglas B.,, Kell, D.B., Gaskell, Simon J, Winder, Catherine L., Malys, Naglis, Dada, J.O., Westerhoff, Hans V.,, Pir, P., Paton, N.W., Pendes, Pedro, Pir, Pınar,, Murabito, Ettore,, Messiha, H.L., Paton, Norman W., Westerhoff, Hans V., Gaskell, Simon J., Dunn, Warwick B.,, Simeonidis, E., Kell, Douglas B., Simeonidis, Evangelos,, Khan, Farid,, Jameson, Daniel; id_orcid, Gaskell, S.J., Jameson, Daniel, Dada, Joseph O, Carroll, Kathleen M.,, Kell, Douglas B, Smallbone, K., Winder, Catherine L, Mendes, P., McCarthy, John E. G., Hayes, Neil W., Paton, Norman; id_orcid, Spasic, Irena, Weichart, Dieter, Pir, Pınar, Gaskell, S. J., Carroll, Kathleen M., Dunn, W.B., Jameson, Daniel,, Jameson, D., Gaskell, Simon J.,, Malys, N., Paton, Norman W.,, Malys, Naglis,, SIMEONIDIS, Vangelis, Smallbone, Kieran,, Simeonidis, Evangelos, Wishart, J., Messiha, Hanan L, Wishart, Jill,, Westerhoff, Hans V, McCarthy, John E G,, Murabito, E., Khan, F., Oliver, Stephen G, Wishart, Jill, Broomhead, David S, Messiha, Hanan L., Dunn, Warwick B, Winder, C.L., Jameson, D,, Dada, Joseph O.,, Swainston, Neil,, Weichart, Dieter,, Oliver, S. G., Hayes, N.W., Pir, Pinar, Spasić, Irena,, Broomhead, D.S., Mendes, Pedro,, Broomhead, David S.,, McCarthy, John E.G., Hayes, Neil W, Hayes, Neil W.,, Oliver, S.G., Swainston, Neil, Smallbone, Kieran, McCarthy, J.E.G., Winder, Catherine L.,, Westerhoff, H.V., Carroll, Kathleen M; id_orcid, Spasic, I.   +99 more
core   +2 more sources

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Research Progress on Glycolysis Mechanism of Psoriasis [PDF]

Lu Wei,1 Buxin Zhang,2 Yuanhui Tu,2 Aimin Liu1,2 1The Second Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, People’s Republic of China; 2Department of Dermatology, Henan Province Hospital of Traditional Chinese Medicine
Liu A, Zhang B, Tu Y, Wei L
core  

Fatal attraction in glycolysis: how Saccharomyces cerevisiae manages sudden transitions to high glucose

, 2015
In the model eukaryote Saccharomyces cerevisiae, it has long been known that a functional trehalose pathway is indispensable for transitions to high glucose conditions. Upon addition of glucose, cells with a defect in trehalose 6-phosphate synthase (Tps1)
Joseph J. Heijnen, Johan H. van Heerden, Bas Teusink, Tom G. O’Toole, Yves J.M. Bollen, Robert Planqué, Frank J. Bruggeman, Josephus Hulshof, Meike T. Wortel, S. Aljoscha Wahl   +9 more
core   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

Advanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun, Hengjie Xu, Sheng Yang, Jiahui Zhou, Chuanxin Tian, Hongxu Nie, Chi Jin, Tuo Wang, Zhihao Chen, Junwei Tang, Yifei Feng, Xiaowei Wang, Yueming Sun   +12 more
wiley   +1 more source

Glycolysis in polycystic ovary syndrome: pathogenesis and treatment

Journal of Ovarian Research
Polycystic ovary syndrome (PCOS) is a common gynaecological endocrine disorder that affects women of reproductive age and is often accompanied by clinical symptoms such as acne, obesity, menstrual disorders, and ovulation disorders.
Liwei Xing, Mingqin Shi, Zhifeng Wang, Huifang Gao, Danyang Li, Rui Guo, Xiaona Zhou, Yang Chen, Jinlong Xu, Zekai Liang, Tie Li, Ke Zhang, Hua Shi, Jian Wang, Ruirui Wang, Rong Zhao   +15 more
doaj   +1 more source

glycolysis and gluconeogenesis-png

, 2014
glycolysis and ...
Karen Fugate (480954)
core   +1 more source