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Aerobic Glycolysis: Beyond Proliferation [PDF]

open access: yesFrontiers in Immunology, 2015
Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review we will discuss some recent findings to illustrate
William Jones, Katiuscia Bianchi
exaly   +7 more sources

Aerobic Glycolysis: A DeOxymoron of (Neuro)Biology [PDF]

open access: yesMetabolites, 2022
The term ‘aerobic glycolysis’ has been in use ever since Warburg conducted his research on cancer cells’ proliferation and discovered that cells use glycolysis to produce adenosine triphosphate (ATP) rather than the more efficient oxidative ...
Avital Schurr, Salvatore Passarella
doaj   +4 more sources

A bioenergetic understanding of “aerobic glycolysis”

open access: yesCommunications Biology
“Aerobic glycolysis” is a widely used term whose current meaning has drifted from its original usage in a way that has created confusion and inaccuracy. This drift has weakened “aerobic glycolysis” as a hypothesis-testing framework, despite the critical ...
Valerie L. Wasem, Shona A. Mookerjee
doaj   +2 more sources

The role and mechanism of aerobic glycolysis in nasopharyngeal carcinoma [PDF]

open access: yesPeerJ
This review delves into the pivotal role and intricate mechanisms of aerobic glycolysis in nasopharyngeal carcinoma (NPC). NPC, a malignancy originating from the nasopharyngeal epithelium, displays distinct geographical and clinical features. The article
Zhiyong Pan   +10 more
doaj   +4 more sources

Role of glycolysis in retinal vascular endothelium, glia, pigment epithelium, and photoreceptor cells and as therapeutic targets for related retinal diseases [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
Glycolysis produces large amounts of adenosine triphosphate (ATP) in a short time. The retinal vascular endothelium feeds itself primarily through aerobic glycolysis with less ATP.
Ting-Ting Yang, Hui Li, Li-Jie Dong
doaj   +1 more source

Comprehensive analysis of aerobic glycolysis-related genes for prognosis, immune features and drug treatment strategy in prostate cancer

open access: yesFrontiers in Oncology, 2022
BackgroundThe dysregulated expression of aerobic glycolysis-related genes is closely related to prostate cancer progression and metastasis. However, reliable prognostic signatures based on aerobic glycolysis have not been well established.MethodsWe ...
Wei He, Xiang He, Enhui Li
doaj   +1 more source

Cancer-Secreted Exosomal MiR-620 Inhibits ESCC Aerobic Glycolysis via FOXM1/HER2 Pathway and Promotes Metastasis

open access: yesFrontiers in Oncology, 2022
BackgroundEsophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide. MicroRNAs (MiRNAs) have been reported to regulate cell functions through exosomes.
Yanbo Zhu   +12 more
doaj   +1 more source

SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis

open access: yesFrontiers in Cell and Developmental Biology, 2022
Increased dependence on aerobic glycolysis is characteristic of most cancer cells, whereas the mechanism underlying the promotion of aerobic glycolysis in metastatic breast cancer cells under ambient oxygen has not been well understood.
Chenguang Yao   +7 more
doaj   +1 more source

Aerobic Glycolysis in Osteoblasts [PDF]

open access: yesCurrent Osteoporosis Reports, 2014
Osteoblasts, the chief bone-making cells in the body, are a focus of osteoporosis research. Although teriparatide, a synthetic fragment of the human parathyroid hormone (PTH), has been an effective bone anabolic drug, there remains a clinical need for additional therapeutics that safely stimulates osteoblast number and function.
Emel, Esen, Fanxin, Long
openaire   +2 more sources

Metformin alleviates nickel-refining fumes-induced aerobic glycolysis via AMPK/GOLPH3 pathway in vitro and in vivo

open access: yesEcotoxicology and Environmental Safety, 2022
Nickel (Ni) compounds is recognized industrial carcinogen, which could increase the risk of lung cancer in Ni refineries workers. However, the underlying carcinogenic mechanism still remains to elucidate.
Tong Zhang   +9 more
doaj   +1 more source

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