Results 11 to 20 of about 104,202 (300)
Aerobic Glycolysis: A DeOxymoron of (Neuro)Biology [PDF]
Metabolites, 2022 The term ‘aerobic glycolysis’ has been in use ever since Warburg conducted his research on cancer cells’ proliferation and discovered that cells use glycolysis to produce adenosine triphosphate (ATP) rather than the more efficient oxidative ...
Avital Schurr, Salvatore Passarella
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Aerobic glycolysis: beyond proliferation. [PDF]
Frontiers in Immunology, 2015 Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review we will discuss some recent findings to illustrate
William eJones, Katiuscia eBianchi
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Brain aerobic glycolysis and motor adaptation learning [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance A substantial fraction of glucose used by the brain does not enter the oxidative phosphorylation pathway despite the presence of adequate oxygen, a phenomenon known as aerobic glycolysis. Among its several functions, aerobic glycolysis makes substantial contributions to biosynthesis, thus becoming a marker of synaptic plasticity.
Benjamin J, Shannon +5 more
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Proton export upregulates aerobic glycolysis
BMC Biology, 2022 Abstract Introduction Aggressive cancers commonly ferment glucose to lactic acid at high rates, even in the presence of oxygen. This is known as aerobic glycolysis, or the “Warburg Effect.” It is widely assumed that this is a consequence of the upregulation of glycolytic ...
Russell, S +14 more
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Aerobic Glycolysis in Osteoblasts [PDF]
Current Osteoporosis Reports, 2014 Osteoblasts, the chief bone-making cells in the body, are a focus of osteoporosis research. Although teriparatide, a synthetic fragment of the human parathyroid hormone (PTH), has been an effective bone anabolic drug, there remains a clinical need for additional therapeutics that safely stimulates osteoblast number and function.
Emel, Esen, Fanxin, Long
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Mediators of Inflammation, 2021 It has been considered that glucose fluctuation (GF) plays a role in renal injury and is related to diabetic nephropathy (DN) development. But the mechanism is still unclear. Aerobic glycolysis has become a topical issue in DN in recent years.
Xiaomei Fu +6 more
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Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology [PDF]
, 2011 Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
Alexei Vazquez, Zoltán N. Oltvai
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Respiratory Research, 2022 Background Up-regulation of aerobic glycolysis has been reported as a characterization of asthma and facilitates airway inflammation. We has been previously reported that short isoform thymic stromal lymphopoietin (sTSLP) could reduce inflammation in ...
Changhui Yu +10 more
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Frontiers in Molecular Biosciences, 2022 Compared to normal cells, cancer cells generate ATP mainly through aerobic glycolysis, which promotes tumorigenesis and tumor progression. Long non-coding RNAs (LncRNAs) are a class of transcripts longer than 200 nucleotides with little or without ...
Ni Fan +8 more
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WWOX loss activates aerobic glycolysis [PDF]
Molecular & Cellular Oncology, 2014 Cancer cells undergo reprogramming of glucose metabolism to limit energy production to glycolysis-a state known as "aerobic glycolysis." Hypoxia-inducible factor 1 (HIF1α) is a transcription factor that regulates many genes responsible for this switch.
Abu-Remaileh, Muhannad +2 more
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