Results 11 to 20 of about 224,058 (247)
Regional aerobic glycolysis in the human brain [PDF]
Proceedings of the National Academy of Sciences, 2010 Aerobic glycolysis is defined as glucose utilization in excess of that used for oxidative phosphorylation despite sufficient oxygen to completely metabolize glucose to carbon dioxide and water. Aerobic glycolysis is present in the normal human brain at rest and increases locally during increased neuronal activity; yet its many biological functions have
S Neil, Vaishnavi +5 more
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Proton export upregulates aerobic glycolysis [PDF]
BMC Biology, 2022 Abstract Introduction Aggressive cancers commonly ferment glucose to lactic acid at high rates, even in the presence of oxygen. This is known as aerobic glycolysis, or the “Warburg Effect.” It is widely assumed that this is a consequence of the upregulation of glycolytic ...
Russell, S +14 more
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Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa [PDF]
Cell Reports, 2018 Aerobic glycolysis accounts for ∼80%–90% of glucose used by adult photoreceptors (PRs); yet, the importance of aerobic glycolysis for PR function or survival remains unclear.
Lolita Petit +6 more
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PLoS ONE, 2014 Warburg effect, one of the hallmarks for cancer cells, is characterized by metabolic switch from mitochondrial oxidative phosphorylation to aerobic glycolysis.
Jia Liu +6 more
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Role of aerobic glycolysis in genetically engineered mouse models of cancer [PDF]
BMC Biology, 2013 The propensity of cancer cells to convert high levels of glucose to lactate through aerobic glycolysis has been intensively studied in vitro, and is now understood to be a metabolic adaptation that shunts glucose carbons toward building blocks for the ...
Dang Chi V
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Sirt3 regulated apoptosis and aerobic glycolysis during renal interstitial fibrosis [PDF]
Linchuang shenzangbing zazhiObjective To observe the expression of silent information regulator 3 （Sirt3）, detect the level of aerobic glycolysis in renal fibrosis model and explore the role of Sirt3 in renal interstitial fibrosis.
Yong-hong Jian +6 more
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Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step [PDF]
eLife, 2014 Aerobic glycolysis or the Warburg Effect (WE) is characterized by the increased metabolism of glucose to lactate. It remains unknown what quantitative changes to the activity of metabolism are necessary and sufficient for this phenotype.
Alexander A Shestov +10 more
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Serine biosynthesis with one carbon catabolism represents a novel pathway for ATP generation in cells using alternative glycolysis with zero net ATP production [PDF]
, 2011 Recent experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP.
Alexei Vazquez +2 more
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Mediators of Inflammation, 2021 It has been considered that glucose fluctuation (GF) plays a role in renal injury and is related to diabetic nephropathy (DN) development. But the mechanism is still unclear. Aerobic glycolysis has become a topical issue in DN in recent years.
Xiaomei Fu +6 more
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Aerobic glycolysis and lymphocyte transformation [PDF]
Biochemical Journal, 1978 1. The role of enhanced aerobic glycolysis in the transformation of rat thymocytes by concanavalin A has been investigated. Concanavalin A addition doubled [U-14C]glucose uptake by rat thymocytes over 3h and caused an equivalent increased incorporation into protein, lipids and RNA. A disproportionately large percentage of the extra glucose taken up was
Hume, David A. +3 more
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