Results 41 to 50 of about 224,058 (247)

Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS

Cell Communication and Signaling, 2019
Oncogenic KRAS plays a vital role in controlling tumor metabolism by enhancing aerobic glycolysis. Obesity driven by chronic consumption of high-fat diet (HFD) is a major risk factor for oncogenic KRAS-mediated pancreatic ductal adenocarcinoma (PDAC ...
Dan Wang, Yawei Bi, Lianghao Hu, Yongde Luo, Juntao Ji, Albert Z. Mao, Craig D. Logsdon, Ellen Li, James L. Abbruzzese, Zhaoshen Li, Vincent W. Yang, Weiqin Lu   +11 more
doaj   +1 more source

Beta-amyloid monomers drive up neuronal aerobic glycolysis in response to energy stressors

, 2021
Research on cerebral glucose metabolism has shown that the aging brain experiences a fall of aerobic glycolysis, and that the age-related loss of aerobic glycolysis may accelerate Alzheimer's disease pathology.
Santangelo R, Copani A, Giuffrida ML, Tomasello MF, Zimbone S, Satriano C   +5 more
core   +1 more source

Image_4_Cancer-Secreted Exosomal MiR-620 Inhibits ESCC Aerobic Glycolysis via FOXM1/HER2 Pathway and Promotes Metastasis.tif

, 2022
BackgroundEsophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide. MicroRNAs (MiRNAs) have been reported to regulate cell functions through exosomes.
Fang Li (41162), Yanbo Zhu (756923), Liqun Shao (9470807), Dong Jiang (159266), Yunyun Xu (516217), Yilong Wan (12547411), Hansi Liang (10656434), Si Li (375535), Bo Peng (273834)   +8 more
core   +1 more source

Table_1_Cancer-Secreted Exosomal MiR-620 Inhibits ESCC Aerobic Glycolysis via FOXM1/HER2 Pathway and Promotes Metastasis.xlsx

, 2022
BackgroundEsophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide. MicroRNAs (MiRNAs) have been reported to regulate cell functions through exosomes.
Fang Li (41162), Yanbo Zhu (756923), Liqun Shao (9470807), Dong Jiang (159266), Yunyun Xu (516217), Yilong Wan (12547411), Hansi Liang (10656434), Si Li (375535), Bo Peng (273834)   +8 more
core   +1 more source

Dynamic modelling under uncertainty: the case of Trypanosoma brucei energy metabolism [PDF]

, 2012
Kinetic models of metabolism require detailed knowledge of kinetic parameters. However, due to measurement errors or lack of data this knowledge is often uncertain.
Achcar, Fiona,, Kerkhoven Eduard J., Barrett, M.P., Breitling, Rainer, Breitling, R., Fiona Achcar, Breitling, Rainer,, Bakker, Barbara M.; id_orcid, Achcar, Fiona, Achcar, F., Eduard J. Kerkhoven (187101), Fiona Achcar (187100), Breitling Rainer, Bakker Barbara M., SilicoTryp Consortium, Barrett, Michael P., Rainer Breitling (4371), Michael P Barrett, Bakker, B.M., Barbara M. Bakker (102159), Barrett, Michael P.,, Bakker, Barbara M., Barbara M Bakker, Kerkhoven, Eduard J, Matthews, Keith; id_orcid, Kerkhoven, Eduard J.,, Bakker, Barbara M, Rainer Breitling, Barrett, Michael P, Kerkhoven, E.J., ?, ?, Eduard J Kerkhoven, Achcar Fiona, Barrett Michael P., Bakker, Barbara M.,, Kerkhoven, Eduard J., Michael P. Barrett (167748)   +36 more
core   +6 more sources

Image_2_Cancer-Secreted Exosomal MiR-620 Inhibits ESCC Aerobic Glycolysis via FOXM1/HER2 Pathway and Promotes Metastasis.tif

, 2022
BackgroundEsophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide. MicroRNAs (MiRNAs) have been reported to regulate cell functions through exosomes.
Fang Li (41162), Yanbo Zhu (756923), Liqun Shao (9470807), Dong Jiang (159266), Yunyun Xu (516217), Yilong Wan (12547411), Hansi Liang (10656434), Si Li (375535), Bo Peng (273834)   +8 more
core   +1 more source

Aerobic glycolysis tunes YAP/TAZ transcriptional activity [PDF]

, 2015
Increased glucose metabolism and reprogramming toward aerobic glycolysis are a hallmark of cancer cells, meeting their metabolic needs for sustained cell proliferation.
ZANCONATO, FRANCESCA, BRESOLIN, SILVIA, Silvia Bresolin, D. Grifoni, G. Guzzo, E. Enzo, A. Pession, ARAGONA, MARIACELESTE, DUPONT, SIRIO, Pession, Annalisa, Francesca Zanconato, Silvio Bicciato, Guzzo, Giulia, Elena Enzo, Arianna Pocaterra, Grifoni, Daniela, Giulia Santinon, FORCATO, Mattia, BICCIATO, Silvio, SANTINON, GIULIA, Giulia Guzzo, S. Bicciato, POCATERRA, ARIANNA, Mattia Forcato, Sirio Dupont, ENZO, ELENA, Annalisa Pession, Mariaceleste Aragona, M. Forcato, Daniela Grifoni   +29 more
core   +3 more sources

The P2X7 receptor is a key modulator of aerobic glycolysis [PDF]

Cell Death & Disease, 2012
Ability to adapt to conditions of limited nutrient supply requires a reorganization of the metabolic pathways to balance energy generation and production of biosynthetic intermediates. Several fast-growing cells overexpress the P2X7 receptor (P2X7R) for extracellular ATP. A feature of this receptor is to allow growth in the absence of serum.
AMOROSO, Francesca Saveria, FALZONI, Simonetta, ADINOLFI, Elena, FERRARI, Davide, DI VIRGILIO, Francesco   +4 more
openaire   +2 more sources

Image_3_Cancer-Secreted Exosomal MiR-620 Inhibits ESCC Aerobic Glycolysis via FOXM1/HER2 Pathway and Promotes Metastasis.tif

, 2022
BackgroundEsophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide. MicroRNAs (MiRNAs) have been reported to regulate cell functions through exosomes.
Fang Li (41162), Yanbo Zhu (756923), Liqun Shao (9470807), Dong Jiang (159266), Yunyun Xu (516217), Yilong Wan (12547411), Hansi Liang (10656434), Si Li (375535), Bo Peng (273834)   +8 more
core   +1 more source

Research Progress of Warburg Effect in Hepatocellular Carcinoma

Frontiers in Bioscience-Landmark
The Warburg effect, also called aerobic glycolysis, refers to tumor cells that metabolize glucose through glycolysis even in the presence of oxygen. This rapid breakdown of glucose fuels the fast development, growth, and migration of tumor cells. Lactate,
Yanguang Yang, Yuting Gao, Yajun Xiong, Yi Gong, Junlan Lu, Yuman Zhang, Dan Wang, Zhihan Liu, Xinli Shi   +8 more
doaj   +1 more source