Results 21 to 30 of about 224,058 (247)

Short isoform thymic stromal lymphopoietin reduces inflammation and aerobic glycolysis of asthmatic airway epithelium by antagonizing long isoform thymic stromal lymphopoietin

Respiratory Research, 2022
Background Up-regulation of aerobic glycolysis has been reported as a characterization of asthma and facilitates airway inflammation. We has been previously reported that short isoform thymic stromal lymphopoietin (sTSLP) could reduce inflammation in ...
Changhui Yu, Wufeng Huang, Zicong Zhou, Shixiu Liang, Zili Zhou, Jieyi Liu, Haijing Zhao, Laiyu Liu, Hangming Dong, Fei Zou, Shaoxi Cai   +10 more
doaj   +1 more source

Long non-coding RNAs play an important regulatory role in tumorigenesis and tumor progression through aerobic glycolysis

Frontiers in Molecular Biosciences, 2022
Compared to normal cells, cancer cells generate ATP mainly through aerobic glycolysis, which promotes tumorigenesis and tumor progression. Long non-coding RNAs (LncRNAs) are a class of transcripts longer than 200 nucleotides with little or without ...
Ni Fan, Hui Fu, Xuchen Feng, Yatong Chen, Jingyu Wang, Yuqi Wu, Yuhong Bian, Yingpeng Li, Yingpeng Li   +8 more
doaj   +1 more source

NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma

BMC Cancer, 2021
Background Increased expression of the transcription factor Forkhead box M1 (FOXM1) has been reported to play an important role in the progression and development of multiple tumors, but the molecular mechanisms that regulate FOXM1 expression remain ...
Xiangsheng Su, Yihang Yang, Qing Yang, Bo Pang, Shicheng Sun, Yanjun Wang, Qiujiang Qiao, Changfa Guo, Huanting Liu, Qi Pang   +9 more
doaj   +1 more source

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology [PDF]

, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
Vazquez, Alexei, Oltvai Zoltán N., Vazquez, A, Zoltán N Oltvai, Alexei Vazquez, Vazquez Alexei, Oltvai, ZN, Oltvai, Zoltán N., Zoltán N. Oltvai   +8 more
core   +2 more sources

HES1 promotes aerobic glycolysis and cancer progression of colorectal cancer via IGF2BP2-mediated GLUT1 m6A modification

Cell Death Discovery, 2023
Aerobic glycolysis has been shown to play a key role in tumor cell proliferation and metastasis. However, how it is directly regulated is largely unknown.
Jiayu Wang, Mengxin Zhu, Jinghan Zhu, Juntao Li, Xingchao Zhu, Kun Wang, Kanger Shen, Kexi Yang, Xiangyu Ni, Xin Liu, Guangbo Zhang, Qinhua Xi, Tongguo Shi, Weichang Chen   +13 more
doaj   +1 more source

Development of an Aerobic Glycolysis Index for Predicting the Sorafenib Sensitivity and Prognosis of Hepatocellular Carcinoma

Frontiers in Oncology, 2021
Hepatocellular carcinoma (HCC) is a deadly tumor with high heterogeneity. Aerobic glycolysis is a common indicator of tumor growth and plays a key role in tumorigenesis.
Yu Pan, Yu Pan, Yu Pan, Yu Pan, Yu Pan, Yu Pan, Geng-yuan Hu, Geng-yuan Hu, Geng-yuan Hu, Shi Jiang, Shi Jiang, Shi Jiang, Shi Jiang, Shi Jiang, Shi Jiang, Shun-jie Xia, Shun-jie Xia, Shun-jie Xia, Shun-jie Xia, Shun-jie Xia, Shun-jie Xia, Hendi Maher, Hendi Maher, Hendi Maher, Hendi Maher, Hendi Maher, Hendi Maher, Zhong-jie Lin, Zhong-jie Lin, Zhong-jie Lin, Zhong-jie Lin, Zhong-jie Lin, Zhong-jie Lin, Qi-jiang Mao, Qi-jiang Mao, Qi-jiang Mao, Qi-jiang Mao, Qi-jiang Mao, Qi-jiang Mao, Jie Zhao, Jie Zhao, Jie Zhao, Jie Zhao, Jie Zhao, Liu-xin Cai, Liu-xin Cai, Liu-xin Cai, Liu-xin Cai, Liu-xin Cai, Ying-hua Xu, Jun-jie Xu, Jun-jie Xu, Jun-jie Xu, Jun-jie Xu, Jun-jie Xu, Xiu-jun Cai, Xiu-jun Cai, Xiu-jun Cai, Xiu-jun Cai, Xiu-jun Cai   +59 more
doaj   +1 more source

WWOX loss activates aerobic glycolysis [PDF]

Molecular & Cellular Oncology, 2014
Cancer cells undergo reprogramming of glucose metabolism to limit energy production to glycolysis-a state known as "aerobic glycolysis." Hypoxia-inducible factor 1 (HIF1α) is a transcription factor that regulates many genes responsible for this switch.
Abu-Remaileh, Muhannad, Seewaldt, Victoria L, Aqeilan, Rami I   +2 more
openaire   +2 more sources

Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect [PDF]

, 2011
The Warburg effect - a classical hallmark of cancer metabolism - is a counter-intuitive phenomenon in which rapidly proliferating cancer cells resort to inefficient ATP production via glycolysis leading to lactate secretion, instead of relying primarily ...
Tomer Shlomi, Eyal Gottlieb, Gottlieb, E., Shlomi, T., Gottlieb Eyal, Roded Sharan, Eytan Ruppin, Ruppin Eytan, Tomer Benyamini, Shlomi Tomer, Sharan Roded, Benyamini Tomer, Ruppin, E., Benyamini, T., Sharan, R.   +14 more
core   +1 more source

Quercetin Antagonizes Glucose Fluctuation Induced Renal Injury by Inhibiting Aerobic Glycolysis via HIF-1α/miR-210/ISCU/FeS Pathway

Frontiers in Medicine, 2021
Background and Objective: Glucose fluctuation (GF) has been reported to induce renal injury and diabetic nephropathy (DN). However, the mechanism still remains ambiguous.
Wei-long Xu, Su Liu, Nan Li, Li-fang Ye, Min Zha, Chang-yin Li, Yue Zhao, Qiang Pu, Jin-jing Bao, Xing-jie Chen, Jiang-yi Yu, Ying-hao Pei   +11 more
doaj   +1 more source

The Role of Aerobic Glycolysis in the Resting Human Brain [PDF]

, 2010
The human brain accounts for 2% of total body weight, though it consumes 20% of the body\u27s energy supply. Most of this energy is provided by the complete oxidation of glucose to carbon dioxide and water, though some fraction of glucose undergoes ...
Vaishnavi, Sanjeev
core   +1 more source