Results 101 to 110 of about 339,187 (240)

m6A-dependent glycolysis enhances colorectal cancer progression

Molecular Cancer, 2020
Epigenetic alterations are involved in various aspects of colorectal carcinogenesis. N6-methyladenosine (m6A) modifications of RNAs are emerging as a new layer of epigenetic regulation.
Chao-qin Shen, Baoqin Xuan, Tingting Yan, Yanru Ma, Pingping Xu, Xianglong Tian, Xinyu Zhang, Yingying Cao, Dangdang Ma, Xiaoqiang Zhu, Youwei Zhang, J. Fang, Haoyan Chen, Jie Hong   +13 more
semanticscholar   +1 more source

Bistability in glycolysis pathway as a physiological switch in energy metabolism.

PLoS ONE, 2014
The flux of glycolysis is tightly controlled by feed-back and feed-forward allosteric regulations to maintain the body's glucose homeostasis and to respond to cell's growth and energetic needs.
Bhanu Chandra Mulukutla, Andrew Yongky, Prodromos Daoutidis, Wei-Shou Hu   +3 more
doaj   +1 more source

Glycolysis

Citation: 'glycolysis' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10774 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
K.O. Honikel, E. Puolanne
  +5 more sources

Modeling of the Glycolysis Pathway in Plasmodium falciparum using Petri Nets [PDF]

, 2016
Malaria is one of the deadly diseases, which affects a large number of the world’s population. The Plasmodium falciparum parasite during erythrocyte stages produces its energy mainly through anaerobic glycolysis, with pyruvate being converted into ...
Rotimi, Solomon, Oyelade, O. J., Okunoren, Ifeoluwa, Ifeoluwa Okunoren, Isewon, Itunuoluwa, Itunuoluwa Isewon, Solomon Rotimi, Jelili Oyelade   +7 more
core  

Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity

Science, 2018
Immunometabolism as therapeutic target Dimethyl fumarate (DMF) is an immunomodulatory compound used to treat multiple sclerosis and psoriasis whose mechanisms of action remain only partially understood. Kornberg et al.
M. Kornberg, P. Bhargava, Paul M. Kim, V. Putluri, A. Snowman, N. Putluri, P. Calabresi, S. Snyder   +7 more
semanticscholar   +1 more source

From steady-state to synchronized yeast glycolytic oscillations I: Model construction

, 2012
ArticleAn existing detailed kinetic model for the steady-state behavior of yeast glycolysis was tested for its ability to simulate dynamic behavior. Using a small subset of experimental data, the original model was adapted by adjusting its parameter ...
Snoep J.L., Kooi B., Rohwer J.M., Du Preez F.B., Van Niekerk D.D.   +4 more
core   +1 more source

Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa

Cell Reports, 2018
Aerobic glycolysis accounts for ∼80%–90% of glucose used by adult photoreceptors (PRs); yet, the importance of aerobic glycolysis for PR function or survival remains unclear.
Lolita Petit, Shan Ma, Joris Cipi, Shun-Yun Cheng, Marina Zieger, Nissim Hay, Claudio Punzo   +6 more
doaj   +1 more source

Hemin Prevents Increased Glycolysis in Macrophages upon Activation: Protection by Microbiota-Derived Metabolites of Polyphenols

, 2020
Meat consumption plays a critical role in the development of several types of cancer. Hemin, a metabolite of myoglobin produced after meat intake, has been demonstrated to be involved in the cancer initiation phase.
Avery, VM, Vicky M. Avery, Catalina Carrasco-Pozo, Tan, KN, Carrasco-Pozo, C, Kah Ni Tan   +5 more
core   +1 more source

Isoscopoletin inhibits hepatocellular carcinoma cell proliferation via regulating glycolysis-related proteins.

PLoS ONE
ObjectiveIsoscopoletin is one of the primary metabolites of natural product scoparone, which was reported to against tumor proliferation. The aim of this study was to explore the mechanism of isoscopoletin against hepatocellular carcinoma (HCC ...
Chenyao Ruan, Chen Wang, Jiawen Gu, Zhihui Zhu   +3 more
doaj   +1 more source

TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemia

Journal of Hematology & Oncology, 2016
Background Cancer cells show increased glycolysis and take advantage of this metabolic pathway to generate ATP. The TP53-induced glycolysis and apoptosis regulator (TIGAR) inhibits aerobic glycolysis and protects tumor cells from intracellular reactive ...
Sixuan Qian, Jianyong Li, Ming Hong, Yu Zhu, Huihui Zhao, Yue Xie, Jiayu Huang, Yun Lian, Yanru Li, Shuai Wang, Jianping Mao, Yaoyu Chen   +11 more
doaj   +1 more source