Results 141 to 150 of about 226,351 (284)

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

Glycolysis-Driven Immune Subtypes in the Tumor Microenvironment Determine Clinical Outcomes in Diffuse Large B-Cell Lymphoma. [PDF]

Cancers (Basel)
Du Y, Liu Z, Liu C, Yuan Y, Fang M, Zhou T, Pan M, Xu W, Liu X, Xu P.   +9 more
europepmc   +1 more source

Supplementary Figure 4 from Caveolin-1 Increases Aerobic Glycolysis in Colorectal Cancers by Stimulating HMGA1-Mediated <i>GLUT3</i> Transcription

, 2023
Tae‐Kyu Ha, Nam-Gu Her, Min Goo Lee, Byung–Kyu Ryu, Jinhee Lee, Jikhyon Han, Seong-In Jeong, Min Ju Kang, Nam Hoon Kim, Hyo Jong Kim, Sung-Gil Chi   +10 more
openalex   +1 more source

All‐Round Talent: Unique Zinc Guanidine Catalyst Performs Efficiently in Synthesis and Chemical Recycling of (Bio)Polyesters

Advanced Science, EarlyView.
A new zinc hybrid guanidine catalyst [Zn{(R,R)TMGNMe2(1,2)ch}2](OTf)2 (C1) shows very high catalytic activity in the polymerization of cyclic esters and in the depolymerization of these polyesters. Using C1 in the ring‐opening polymerization of lactide and caprolactone under industrially relevant conditions, astonishing rate constants of the same order
Tabea Becker, Koki Takeuchi, Carolin Süßmuth, Frederico Boekhoff, Martin A. Schäfer, Shunsuke Kato, Alexander Hoffmann, Takashi Hayashi, Sonja Herres‐Pawlis   +8 more
wiley   +1 more source

Research progress on glycolytic reprogramming in ophthalmic diseases. [PDF]

PeerJ
Gong X, Feng J, Han Y, Tang G, Yin Y, Li J, Liu Y, Zhang J, Song J, Bi H.   +9 more
europepmc   +1 more source

LncRNA ACVR2B-as1 interacts with ALDOA to regulate the self-renewal and apoptosis of human spermatogonial stem cells by controlling glycolysis activity [PDF]

Zhipeng Xu, Cai Lv, Jun Gao, Yinghong Cui, Wei Liu, Zuping He, Leye He   +6 more
openalex   +1 more source

Supplementary Figure 3 from Proliferation-Independent Control of Tumor Glycolysis by PDGFR-Mediated AKT Activation

, 2023
Cong Ran, Huan Liu, Yasuyuki Hitoshi, Mark A. Israel   +3 more
openalex   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

SLC16A3 in lung adenocarcinoma regulates glycolysis and lactate release to facilitate M2 polarization of tumor-associated macrophages : Short Title: SLC16A3 reinforces macrophage M2 polarization through glycolysis. [PDF]

Cancer Immunol Immunother
Chen P, Qing Q, Gao H, Qin Z, Lv J.
europepmc   +1 more source

Figure S4 from Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression

, 2023
Dhruv Kumar, Jacob New, Vikalp Vishwakarma, Radhika Joshi, Jonathan Enders, Fangchen Lin, Sumana Dasari, Wade R. Gutierrez, George Leef, Sivapriya Ponnurangam, Hemantkumar Chavan, Lydia Ganaden, Mackenzie Thornton, Hongying Dai, Ossama Tawfik, Jeffrey Straub, Yelizaveta Shnayder, Kiran Kakarala, Terance T. Tsue, Douglas A. Girod, Bennett Van Houten, Shrikant Anant, Partha Krishnamurthy, Sufi M. Thomas   +23 more
openalex   +1 more source