Results 151 to 160 of about 422,950 (380)

AN EXPERIMENTAL STUDY OF BLOOD GLYCOLYSIS. THE EFFECTS OF THYROID AND ADRENAL EXTRACTS AND PHLORHIZIN ON GLYCOLYSIS IN VITRO [PDF]

, 1915
G. M. Mackenzie
openalex   +1 more source

Peptide Coacervates with Metal–Phenolic Membranes Modulate Glucose Metabolism and Enhance Cancer Immunotherapy

Advanced Materials, EarlyView.
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng, Shiqiong Lei, Yiwei Zeng, Lian Chen, Jingqu Chen, Wei Fu, Yu Chen, Xinping Hu, Jing Wang, Meiyuan Jin, Zhichen Liu, Xiaofang Dai, Lei Liu, Wenshan He, Jiajing Zhou, Zhixing Lin, Frank Caruso, Jinghua Ren   +17 more
wiley   +1 more source

HIF-1α regulated GLUT1-mediated glycolysis enhances Treponema pallidum-induced cytokine responses

Cell Communication and Signaling
Syphilis, caused by Treponema pallidum (Tp), represents a significant public health challenge. The clinical manifestations of syphilis are attributed to local inflammatory responses induced by Tp, notably monocyte infiltration into local lesions and the ...
Shun Xiong, Zhaoping Liu, Jiangchen Yao, Shaobin Huang, Xuan Ding, Han Yu, Ting Lin, Xiaohong Zhang, Feijun Zhao   +8 more
doaj   +1 more source

An experimental enquiry upon glycolysis in drawn blood [PDF]

, 1902
F. W. Pavy, R. L. Siau
openalex   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Citrate‐Enhanced PCL Scaffolds for Bone Tissue Engineering

Advanced Materials Interfaces, EarlyView.
This study investigates citrate‐enhanced polycaprolactone (PCL) scaffolds designed for bone tissue engineering. Utilizing 3D printing technology, four scaffold patterns (triple hexagon, grid, gyroid, zigzag) are evaluated for mechanical properties, cellular proliferation, osteogenic differentiation, and gene expression.
Muge Musmula, Oguz Sogut, Basak Aru, Gizem Gurel, Serdar Sezer, Gulderen Yanıkkaya Demirel, Umran Aydemir Sezer   +6 more
wiley   +1 more source

NSUN5 accelerates the progression of liver hepatocellular carcinoma by m5C-EFNA3-mediated glycolysis

BMC Cancer
Background Aerobic glycolysis is a hallmark of cancers including liver hepatocellular carcinoma (LIHC). RNA m5C methylation is involved in LIHC progression. However, the effect of a m5C writer, NSUN5, on glycolysis in LIHC remains not known.
Yehong Han, Xueqin Deng, Haixia Chen, Jie Chen, Wei Xu, Lanqin Liu   +5 more
doaj   +1 more source

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Advanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu, Jingyi Liu, Wei Qin, Chengsheng Ding, Zhenghao Cai, Duohuo Shu, Hao Zhong, Yanyan Hu, Mengqin Yu, Leqi Zhou, Jianwen Li, Minhua Zheng, Bin Li, Sen Zhang, Xiao Yang, Bo Feng   +15 more
wiley   +1 more source

Growth and Aerobic Glycolysis in the Retina of the Chicken Embryo [PDF]

, 1952
Richard J. O’Connor
openalex   +1 more source

Branched‐Chain α Keto‐Acid Dehydrogenase Kinase‐Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance

Advanced Science, EarlyView.
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian, Jinxiang Wang, Qiji Li, Yangruiyu Liu, Yanping Chen, Jiacheng Feng, Zi‐Ning Lei, Harsh Patel, Chao‐Yun Cai, Yuzhi Xu, Chuntao Quan, Lingyan Fei, Zexiu Xiao, Shuo Fang, Tianxin Lin, Zhe‐Sheng Chen, Yuchen Liu, Leli Zeng, Yihang Pan   +18 more
wiley   +1 more source