Results 241 to 250 of about 410,307 (399)

Activation of sclerostin inhibits Isg20-Mediated aerobic glycolysis ameliorating renal Fibrosis: the renoprotective mechanism of hederagenin in CKD. [PDF]

Redox Biol
Han RY, Tan RZ, Xu LH, Lin JY, Li T, Su HW, Li P, Liu P, Lan HY, Wang L.   +9 more
europepmc   +1 more source

FACTORS AFFECTING HEPATIC GLYCOLYSIS AND SOME CHANGES THAT OCCUR DURING DEVELOPMENT [PDF]

, 1965
Michael A. Lea, DG Walker
openalex   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source

CypA inhibits respiratory syncytial virus (RSV) replication by suppressing glycolysis through the downregulation of PKM2 expression. [PDF]

J Virol
Zhang J, Li M, Cheng J, Wang Y, Ma C, Yin L, Wang J, Gao X, Liang W, Wei L.   +9 more
europepmc   +1 more source

The influence of potassium on respiration and glycolysis by brain slices [PDF]

, 1962
K. A. C. Elliott, Fernand Bilodeau
openalex   +1 more source

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Science, 2014
Shih-Chin Cheng, J. Quintin, R. Cramer, K. Shepardson, Sadia Saeed, Vinod Kumar, E. Giamarellos‐Bourboulis, J. Martens, Nagesha A S Rao, A. Aghajanirefah, G. Manjeri, Yang Li, D. Ifrim, R. Arts, Brian M. J. W. van der Veer, P. Deen, C. Logie, L. O’Neill, P. Willems, F. L. van de Veerdonk, J. V. D. van der Meer, Aylwin Ng, L. Joosten, C. Wijmenga, H. Stunnenberg, R. Xavier, M. Netea   +26 more
semanticscholar   +1 more source

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu, Zhihuang Zheng, Marleen Silke Oswald, Guozhe Cheng, Jun Liu, Qidi Zhai, Ute Kruegel, Michael Schaefer, Holger Gerhardt, Nicole Endlich, Maik Gollasch, Stefan Simm, Dmitry Tsvetkov   +12 more
wiley   +1 more source

Integration RNA bulk and single cell RNA sequencing to explore the change of glycolysis-related immune microenvironment and construct prognostic signature in head and neck squamous cell carcinoma

Translational Oncology
Background: Glycolysis is an indispensable process for tumor cell,but the effect of glycolysis on the prognosis and immune cell infiltration of head and neck squamous cell carcinoma is not clear.
Qian Nie, Huan Cao, Jianwang Yang, Tao Liu, Baoshan Wang   +4 more
doaj  

SMAD3 and HIF-1α orchestrate metabolic transition to aerobic glycolysis as a critical prerequisite for spontaneous reprogramming of spermatogonial stem cells. [PDF]

Stem Cell Res Ther
Cai Y, Wen J, Liu H, Wei R, Li X, Dong Y, Cheng K, Zou K.   +7 more
europepmc   +1 more source

NDRG1‐Driven Lactate Accumulation Promotes Lung Adenocarcinoma Progression Through the Induction of an Immunosuppressive Microenvironment

Advanced Science, EarlyView.
NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu, Hongxia Cheng, Jiacheng Yin, Yuansheng Zheng, Haochun Shi, Binyang Pan, Ming Li, Mengnan Zhao, Jiaqi Liang, Yunyi Bian, Guangyao Shan, Guoshu Bi, Weigang Guo, Lin Wang, Yiwei Huang   +14 more
wiley   +1 more source