Results 231 to 240 of about 291,093 (299)

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

T-cell metabolic reprogramming in systemic lupus erythematosus: linking intracellular metabolism to effector differentiation and senescent-like/exhausted-like states. [PDF]

Front Immunol
Zou Y, Ren Z, Kudo Y, Kono M.
europepmc   +1 more source

pH‐Responsive Nanoplatform‐Mediated Lipid Hijacking and Metabolic Collapse for Synergistic Starvation‐Immunotherapy

Advanced Science, EarlyView.
A pH‐responsive ZIF‐8/2‐DG@Cu‐TA nanoplatform orchestrates multifaceted metabolic disruption for synergistic starvation‐immunotherapy. Acid‐triggered 2‐DG release blocks glycolysis, while Zn2+ overload induces mitochondrial dysfunction. Concurrently, Cx43‐mediated gap junctions redirect lipid droplets from tumor cells to cancer‐associated fibroblasts ...
Xianlong Zong, Haochen Yao, Danyang Shen, Furu Gong, Zixuan Wang, Haoyang Qin, Yang Yang, Ruirui Qiao, Yongjuan Li, Rui Li   +9 more
wiley   +1 more source

Single-cell and bulk transcriptomic analysis of inflammation-metabolism programs and the tumor microenvironment of colorectal cancer liver metastasis. [PDF]

Transl Oncol
Ma Z, Jiang W, Zhang J, Kong L, Zhao C, Ma F, Wu C.   +6 more
europepmc   +1 more source

Glycolytic reprogramming in precancerous lesions of gastric cancer progression: pathogenesis and therapeutic potential. [PDF]

Front Oncol
Niu S, Sun H, Wang Z, Jin Q, Sun Z, Yu D, Zhang Y.   +6 more
europepmc   +1 more source

Ionic-Liquid-Catalyzed Depolymerization of PET: BHET Recovery and Re-Polymerization. [PDF]

Polymers (Basel)
Karayev A, Shehzad F, Mazhar H, Al-Harthi MA.   +3 more
europepmc   +1 more source

OLFM4 promotes intrahepatic cholangiocarcinoma progression through a PKM2-glycolysis-histone lactylation feedback loop. [PDF]

Int J Biol Sci
Liu S, Cao K, Chen C, Xu X, Shan J, Li C, Chen R, Chen Y, Chang J, Jiang W, Zhang Y, Wang D, Li C, Li X.   +13 more
europepmc   +1 more source