Results 31 to 40 of about 56,998 (309)
Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance [PDF]
, 2020 Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
Anderson, Rosaleen +8 more
core +2 more sources
Synthesis of glycosylated β3-homo-threonine conjugates for mucin-like glycopeptide antigen analogues
Beilstein Journal of Organic Chemistry, 2010 Glycopeptides from the mucin family decorated with tumour-associated carbohydrate antigens (TACA) have proven to be important target structures for the development of molecularly defined anti-cancer vaccines.
Florian Karch, Anja Hoffmann-Röder
doaj +1 more source
Risk factors for failure of outpatient parenteral antibiotic therapy (OPAT) in infective endocarditis [PDF]
, 2013 Objectives: To identify risk factors for failure of outpatient antibiotic therapy (OPAT) in infective endocarditis (IE). Patients and methods: We identified IE cases managed at a single centre over 12 years from a prospectively maintained database. ‘
Barr, D. A. +5 more
core +1 more source
Biomolecules, 2015 Neutrophil cathepsin G (nCG) is a central serine protease in the human innate immune system, but the importance of its N-glycosylation remains largely undescribed.
Ian Loke +2 more
doaj +1 more source
Antibiotics, 2022 Antibiotic treatment strategies for fracture-related infections (FRI) are often extrapolated from periprosthetic joint infections (PJI), although, in contrast to PJI, detailed analysis of pathogens and their antibiotic resistance is missing.
Susanne Baertl +6 more
doaj +1 more source
Protein O-Mannosylation in the Murine Brain: Occurrence of Mono-O-Mannosyl Glycans and Identification of New Substrates [PDF]
, 2016 Protein O-mannosylation is a post-translational modification essential for correct development of mammals. In humans, deficient O-mannosylation results in severe congenital muscular dystrophies often associated with impaired brain and eye development ...
Bartels, MF +10 more
core +5 more sources
National Journal of Laboratory Medicine, 2023 Introduction: Staphylococcus aureus (S. aureus) is a ubiquitous pathogen causing various infections in humans. The emergence of drug resistance in S. aureus, especially methicillin resistance, has made treating these infections increasingly tricky, with ...
Thammina Meher Srisai Sudhavani +3 more
doaj +1 more source
Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]
, 2014 Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce +6 more
core +1 more source
Synthesis and In Vitro Characterization of Glycopeptide Drug Candidates Related to PACAP1–23
Molecules, 2021 The search for efficacious treatment of neurodegenerative and progressive neuroinflammatory diseases continues, as current therapies are unable to halt or reverse disease progression.
Christopher R. Apostol +6 more
doaj +1 more source
Discovery of Serotransferrin Glycoforms: Novel Markers for Diagnosis of Liver Periductal Fibrosis and Prediction of Cholangiocarcinoma. [PDF]
, 2019 Cholangiocarcinoma (CCA) caused by chronic liver fluke infection is a major public health problem in Northeast Thailand. Identification of CCA risk groups is urgently needed for the control of CCA in this region.
Barboza, Mariana +10 more
core +2 more sources