Results 51 to 60 of about 15,705 (221)

Enhanced Detection of Multiple Myeloma Cells by Next‐Generation Flow Cytometry Following Density Gradient Medium Separation

European Journal of Haematology, Volume 116, Issue 3, Page 256-266, March 2026.
ABSTRACT Introduction Following treatment, relapse of Multiple Myeloma (MM) occurs due to measurable residual disease (MRD). As therapeutic options expand, advances in response assessment become more critical, necessitating more sensitive MRD detection methods.
Aisling O'Brien, Vitaliy Mykytiv, Fiona O'Halloran   +2 more
wiley   +1 more source

Phenotypic features of erythrocytes and activity of erythropoiesis in cardiosurgical patients with various degree of postperfusion hemolysis manifestation

Бюллетень сибирской медицины, 2012
A study of phenotypic characteristics of erythrocytes and indicators of activity of erythropoiesis in cardiosurgical patients with moderated (40 patients) and expressed (18 patients) hemolysis after coronary artery bypass grafting in conditions of ...
V. V. Novitsky, S. P. Chumakova, O. I. Urazova, V. M. Shipulin, O. A. Khokhlov, Yu. V. Kolobovnikova   +5 more
doaj   +1 more source

Human natural killer cell committed thymocytes and their relation to the T cell lineage. [PDF]

, 1993
Recent studies have demonstrated that mature natural killer (NK) cells can be grown from human triple negative (TN; CD3-, CD4-, CD8-) thymocytes, suggesting that a common NK/T cell precursor exists within the thymus that can give rise to both NK cells ...
Lanier, LL, Phillips, JH, Spits, H, Sánchez, MJ   +3 more
core   +1 more source

Gene Regulatory Programs of NK Cells Show That NCAM1 (CD56) and KIRs Are Controlled by Genetically Polymorphic Distal Regulatory Elements

European Journal of Immunology, Volume 56, Issue 2, February 2026.
A deeper understanding of the natural killer cell gene expression regulation driving NK cell maturation and cytotoxicity could provide critical insights into optimizing NK therapies. Our findings reveal novel enhancers governing NK cell genes for NCAM1/CD56 and cis‐regulation for KIR receptors and clarify existing models of NK cell cis‐accessibility ...
Mariam A. Salem, Aditi Varkey, Matthew D. Estrada, Kruthika Sharma, Caprice D. Eisele, Nitin Chakravarti, Dean A. Lee, Aharon G. Freud, Bethany L. Mundy‐Bosse, Patrick L. Collins   +9 more
wiley   +1 more source

Morphologic and immunophenotypic features of a case of acute monoblastic leukemia with unusual positivity for Glycophorin-A

Hematology Reports, 2018
Acute monoblastic leukemia (AMoL) is characterized by cells with highly undifferentiated morphology. Cytochemistry with non-specific esterases is negative in up to 20% of cases. Immunophenotyping by flow cytometry has an essential role in diagnosing such
Giovanni Carulli, Paola Sammuri, Cristiana Domenichini, Martina Rousseau, Virginia Ottaviano, Maria Immacolata Ferreri, Antonio Azzarà, Francesco Caracciolo, Mario Petrini   +8 more
doaj   +1 more source

Isolation and characterization of a laminin-binding protein from rat and chick muscle. [PDF]

, 1988
A major laminin-binding protein (LBP), distinct from previously described LBPs, has been isolated from chick and rat skeletal muscle (Mr 56,000 and 66,000, respectively).
Frazer, KA, Hall, DE, Hann, BC, Reichardt, LF   +3 more
core  

Protein S Enhances the Phagocytosis of Phosphatidylserine‐Exposing Erythrocytes: Implications in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 1, Page 26-40, January 2026.
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Claire Auditeau, Aurélie Fricot, Raphaël Gauthier, Abdoulaye Sissoko, Zeynep Cacan, Céline Gounou, Laure Joseph, Sandra Manceau, Slimane Allali, Michael Dussiot, Mickael Marin, Alexis Lavergne, Mariem Khamari, Sophie Moog, Elsa Bianchini, Laetitia Claer, Sandrine Laurance, Valentine Brousse, Sébastien Eymieux, Philippe Roingeard, Pascal Amireault, Thiago Trovati Maciel, Alain Brisson, Pierre Buffet, François Saller, Delphine Borgel, Camille Roussel   +26 more
wiley   +1 more source

Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis

Haematologica, 2019
AMP-activated protein kinase (AMPK) is a heterotrimeric complex containing α, β, and γ subunits involved in maintaining integrity and survival of murine red blood cells.
Meriem Ladli, Cyrielle Richard, Lilia Cantero Aguilar, Sarah Ducamp, Sabrina Bondu, Pierre Sujobert, Jérôme Tamburini, Catherine Lacombe, Nabih Azar, Marc Foretz, Yael Zermati, Patrick Mayeux, Benoit Viollet, Frédérique Verdier   +13 more
doaj   +1 more source

Wound Vitality in Decomposed Bodies: New Frontiers Through Immunohistochemistry

Frontiers in Medicine, 2021
Background: The question about wound vitality and the estimation of wound age of production are two of the classic investigation fields of forensic sciences. To answer this, the techniques most frequently used in research studies are immunohistochemistry
Giuseppe Bertozzi, Michela Ferrara, Raffaele La Russa, Giovanni Pollice, Giovanni Gurgoglione, Paolo Frisoni, Letizia Alfieri, Stefania De Simone, Margherita Neri, Luigi Cipolloni   +9 more
doaj   +1 more source

MeMAGEN: A Phase IIa/IIb open‐label trial of memantine testing safety and tolerability in sickle cell patients

HemaSphere, Volume 10, Issue 1, January 2026.
ABSTRACT Administration of memantine, an antagonist of the N‐methyl‐ d‐aspartate receptor, prevents Ca2+ overload and dehydration of red blood cells (RBCs) in patients with sickle cell disease (SCD). The objectives of the 1‐year dose‐escalation Phase IIa/IIb Memantine trial (MeMAGEN – NCT 03247218) with 17 SCD patients who were under stable ...
Ariel Koren, Carina Levin, Leonid Livshits, Fabio Valeri, Sari Peretz, Sivan Raz, Anna Yu Bogdanova, Max Gassmann   +7 more
wiley   +1 more source