Results 41 to 50 of about 1,830 (157)

Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis

Haematologica, 2019
AMP-activated protein kinase (AMPK) is a heterotrimeric complex containing α, β, and γ subunits involved in maintaining integrity and survival of murine red blood cells.
Meriem Ladli, Cyrielle Richard, Lilia Cantero Aguilar, Sarah Ducamp, Sabrina Bondu, Pierre Sujobert, Jérôme Tamburini, Catherine Lacombe, Nabih Azar, Marc Foretz, Yael Zermati, Patrick Mayeux, Benoit Viollet, Frédérique Verdier   +13 more
doaj   +1 more source

Mass spectral imaging of glycophospholipids, cholesterol, and glycophorin A in model cell membranes

, 2008
Time of flight secondary ion mass spectrometry (ToF-SIMS) and the Langmuir-Blodgett (LB) technique have been used to create and analyze reproducible membrane mimics of the inner and outer leaflets of a cellular membrane to investigate lipid-protein and ...
Lockyer, Nicholas P., Vickerman, John C., Zheng, Leiliang, Baker, Matthew J., Winograd, Nicholas   +4 more
core   +5 more sources

Expert Consensus on the Diagnosis and Monitoring of Paroxysmal Nocturnal Hemoglobinuria (PNH): An Algorithmic Approach in an Era of New Treatments

European Journal of Haematology, EarlyView.
ABSTRACT Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder caused by a defect of glycosylphosphatidyl‐anchored proteins, leading to an uncontrolled complement‐mediated hemolysis. The advent of complement inhibitors in clinical practice radically changed patients' outcomes and survival.
Bruno Fattizzo, Monia Marchetti, Elisa Cannizzo, Arianna Gatti, Massimo Geuna, Anna Paola Iori, Maddalena Raia, Simona Sica, Francesco Buccisano   +8 more
wiley   +1 more source

TL blotting on Tf and glycophorin.

, 2016
Different amounts of proteins (up to 5 μg) were loaded. The lectin blot analysis indicates that TL does not recognize Tf but reacts with the sialoglycoprotein glycophorin.
David Perez-Morga (104086), Frédéric Fontaine (3058830), Marjorie Vermeersch (2886365), Etienne Pays (256328), Sébastien Brosson (507659), Didier Salmon (507660), Sabrina Bousbata (507661)   +6 more
core   +1 more source

Morphologic and immunophenotypic features of a case of acute monoblastic leukemia with unusual positivity for Glycophorin-A

Hematology Reports, 2018
Acute monoblastic leukemia (AMoL) is characterized by cells with highly undifferentiated morphology. Cytochemistry with non-specific esterases is negative in up to 20% of cases. Immunophenotyping by flow cytometry has an essential role in diagnosing such
Giovanni Carulli, Paola Sammuri, Cristiana Domenichini, Martina Rousseau, Virginia Ottaviano, Maria Immacolata Ferreri, Antonio Azzarà, Francesco Caracciolo, Mario Petrini   +8 more
doaj   +1 more source

Multivalent Bi‐Specific Nanoerythrosomes: A Two‐Birds‐One‐Stone Approach to Combine Homologous and Active Targeting for Effective Thrombolysis

Small, Volume 22, Issue 47, 21 August 2026.
A multivalent bi‐specific nanoerythrosome (mBiNE@tPA) is developed as a “two‐birds‐one‐stone” platform that simultaneously exploits two principal thrombus components. By integrating erythrocyte membrane‐mediated homologous targeting with cRGD‐based active targeting to activated platelets, mBiNE@tPA achieves enhanced thrombus accumulation, triggered ...
Yu Huang, Yilin Yang, Nicole Henry, Boram Gu, Jiahua Wang, Yuanyuan Guo, Colin Longstaff, Simon A. Thom, Yuehua Li, Xiao Yun Xu, Rongjun Chen   +10 more
wiley   +1 more source

Wound Vitality in Decomposed Bodies: New Frontiers Through Immunohistochemistry

Frontiers in Medicine, 2021
Background: The question about wound vitality and the estimation of wound age of production are two of the classic investigation fields of forensic sciences. To answer this, the techniques most frequently used in research studies are immunohistochemistry
Giuseppe Bertozzi, Michela Ferrara, Raffaele La Russa, Giovanni Pollice, Giovanni Gurgoglione, Paolo Frisoni, Letizia Alfieri, Stefania De Simone, Margherita Neri, Luigi Cipolloni   +9 more
doaj   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

The influence of lipid composition on glycophorin-induced bilayer permeability [PDF]

, 1984
(1) Glycophorin was incorporated into large unilamellar vesicles and the bilayer permeability was measured as a function of the lipid composition. (2) In agreement with previous data (Van der Steen, A.T.M., De Kruijff, B. and De Gier, J.
Hoogevest, P. van, Gier, J. de, Kruijff, B. de, Du Maine, A.P.M.   +3 more
core  

Human Platelet‐Derived Extracellular Vesicles Are Internalized by Human Induced Pluripotent Stem Cell‐Derived Neurons Under Control and Hypoxic Conditions

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
Human platelet‐derived extracellular vesicles (EVs) colocalize with cellular organelles, early endosomes and lysosomes, in neurons differentiated from human induced pluripotent stem cells, both in naïve and hypoxic conditions. Furthermore, the functional activity of neurons is changed by hypoxia and by pre‐ and post‐treatment with the EVs in hypoxic ...
Venla Harju, Kai Härkönen, Ulla Impola, Saara Laitinen, Susanna Narkilahti   +4 more
wiley   +1 more source