Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity.
PLoS ONE, 2021 Low plasma levels of Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) are associated with decreased low-density lipoprotein (LDL) cholesterol and a reduced risk of cardiovascular disease.
Rhogerry Deshycka +8 more
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A Comprehensive Review of Our Current Understanding of Red Blood Cell (RBC) Glycoproteins
Membranes, 2017 Human red blood cells (RBC), which are the cells most commonly used in the study of biological membranes, have some glycoproteins in their cell membrane. These membrane proteins are band 3 and glycophorins A–D, and some substoichiometric glycoproteins (e.
Takahiko Aoki
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Brown Recluse spider bite mediated hemolysis: clinical features, a possible role for complement inhibitor therapy, and reduced RBC surface glycophorin A as a potential biomarker of venom exposure. [PDF]
PLoS ONE, 2013 The venom of Loxosceles reclusa (Brown Recluse spider) can cause a severe, life-threatening hemolysis in humans for which no therapy is currently available in the USA beyond supportive measures.
Eric A Gehrie, Hui Nian, Pampee P Young
doaj +1 more source
A Glycophorin A-Like Framework for the Dimerization of Photosynthetic Core Complexes
, 2016 A Glycophorin A-Like Framework for the Dimerization of Photosynthetic Core ...
Klaus Schulten (102849) +2 more
core +6 more sources
Glycophorin B is the Erythrocyte Receptor of Plasmodium Falciparum Erythrocyte-Binding Ligand, EBL-1 [PDF]
, 2014 In the war against Plasmodium, humans have evolved to eliminate or modify proteins on the erythrocyte surface that serve as receptors for parasite invasion, such as the Duffy blood group, a receptor for Plasmodium vivax, and the Gerbich-negative ...
Kabat, Juraj +7 more
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Magnetic resonance study of glycophorin A-containing 13C-enriched methionines [PDF]
, 1982 Methionine-81 and/or -8 of the transmembrane sialoglycoprotein, glycophorin A, have been specifically alkylated with 13CH3I to produce the sulfonium ion derivatives [S-[13C]methylmethionine-8]glycophorin A and [S-[13C]methylmethionine-8 and -81 ...
Hardy, Robert E. +3 more
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Cooperative action between band 3 and glycophorin A in human erythrocytes: immobilization of band 3 induced by antibodies to glycophorin A [PDF]
, 1994 The ability of transmembrane receptor proteins to change their association with the cytoskeleton in response to ligand binding seems to be a key mechanism of signal transduction across membranes. To investigate the molecular features of this mechanism we
Knowles, D.W. +3 more
core +1 more source
Glycophorin-C sialylation regulates Lu/BCAM adhesive capacity during erythrocyte aging
Blood Advances, 2018 : Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5.
T.R.L. Klei +12 more
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Why high intensity plaque is bright on MRI?
American Heart Journal Plus, 2021 Although CT is an excellent imaging modality for detecting lipid pools and calcification in the atherosclerotic plaque, it cannot distinguish hemorrhage from fibrous tissue.
Hajime Sakuma
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Haematologica, 2009 Background Protein 4.1R is an important component of the red cell membrane skeleton. It imparts structural integrity and has transmembrane signaling roles by direct interactions with transmembrane proteins and other membrane skeletal components, notably ...
Kris P. Jeremy +9 more
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