Results 1 to 10 of about 26,591,719 (175)

Dual Maternal Alloimmunization by Antibodies of Rhesus and MNSs Blood Group System: Case Series and Approach to Work Up in a Resource Limited Set Up. [PDF]

Indian J Hematol Blood Transfus
Maternal alloimmunisation by non D Rh and non Rh antibodies leading to HDFN, is a well established problem encountered in Transfusion medicine and poses a serious threat to our health care system. Presence of multiple alloantibodies, especially if one is masking the other, leads to diagnostic dilemma and delay in transfusion therapy of patients.
Pahuja S, Chauhan S, Sharma G, Singh D.
europepmc   +3 more sources

Lcn2 Promotes Ferroptosis in Intracerebral Hemorrhage by Targeting Keap1 Tyr572 and Restricting Nrf2 Activation. [PDF]

MedComm (2020)
This study reveals that Lcn2 regulates ferroptosis after ICH via the Keap1/Nrf2 axis. Neuronal Lcn2 deletion reduces lipid peroxidation, restores mitochondrial function, and improves ferroptosis. Keap1 Tyr572Ala mutant acts as a molecular switch whose effects invert with Lcn2 status.
Dou YN, Hu H, Li Q, Wang G, Hou L, Liu J, Zheng B, Li Y, Hu G, Fei Z, Li X, Wang L, Wei J, Jiang L, Fei X.   +14 more
europepmc   +2 more sources

The MNSs blood group system

The Turkish Journal of Pediatrics, 1967
M Hauge
doaj   +2 more sources

Blood Group Antigens Mia and Vw and their Relation to the MNSs System [PDF]

Nature, 1957
THE blood group antigen Mia was discovered by Levine, Stock, Kuhmichel and Bronikovsky1 in 1951. Anti-Mia, the antibody necessary for the identification of the antigen, was made by a mother in response to immunization by her Mi(a +) fœtus which, as a result, had severe haemolytic disease.
J, WALLACE, G R, MILNE, J, MOHN, R M, LAMBERT, H G, ROSAMILIA, P, MOORES, R, SANGER, R R, RACE   +7 more
openaire   +2 more sources

Molecular analysis of the GYPB gene to infer S, s, and U phenotypes in an admixed population of Minas Gerais, Brazil Análise molecular do gene GYPB para inferência dos fenótipos S, s e U em uma população miscigenada de Minas Gerais - Brasil

Revista Brasileira de Hematologia e Hemoterapia, 2012
OBJECTIVE: To implement genotyping for S, s and U antigens of the MNS blood group system at the Fundação Hemominas and to evaluate the occurrence of GYPB gene polymorphisms associated with the U- and U+var phenotypes and deletion of the GYPB gene for the
Marina Alves Faria, Marina Lobato Martins, Luciana Cayres Schmidt, Maria Clara Fernandes da Silva Malta   +3 more
doaj   +1 more source

Red cell phenotyping of blood from donors at the National blood center of Malaysia

Asian Journal of Transfusion Science, 2012
Background : Human blood groups are polymorphic and inherited integral structures of the red cell membrane. More than 300 red cell antigens have been identified and further categorized into 30 major discrete systems.
Rozi H Musa, Suhair A Ahmed, Hasna Hashim, Yasmin Ayob, Nor H Asidin, Poh Y Choo, Fawwaz S Al-Joudi   +6 more
doaj   +1 more source

The anti-Mia antibody – Report of four cases in a tertiary care hospital with review of literature

Global Journal of Transfusion Medicine, 2019
Anti – Mia antibody is antibody reacting with Mi III phenotype of the Miltenberger (Mi) subsystem. It is rarely reported in the West, however, it is common in Chinese and South East Asian populations. Very few cases have been reported in India.
Sangeeta Pahuja, Shivali Sehgal, Geetika Sharma, Manisha Singh, Ramvilash Yadav   +4 more
doaj   +1 more source

A cross-sectional pilot study to estimate the frequency of minor blood group alleles and phenotypes in RhD-negative North Indian blood donors by DNA microarray analysis

Asian Journal of Transfusion Science
INTRODUCTION: There are scarce data on Indian blood donors with respect to blood group phenotypes using molecular diagnostic modalities. Hence, we planned to estimate frequencies of blood group alleles/phenotypes using DNA microarray analysis in the ...
Gita Negi, Sheetal Malhotra, Bela Goyal, Praveen Kumar Singh, Anissa Atif Mirza   +4 more
doaj   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

Advanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li, Runzhe Huang, Qingyuan Wu, Pengbo Zhou, Dangli Ren, Jingjing Wang, Hanjie Niu, Zemeng Li, Hongtao Sun, Huiyu Liu   +9 more
wiley   +1 more source