Results 231 to 240 of about 1,068,824 (393)

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

open access: yesScience, 2013
J. McLellan   +27 more
semanticscholar   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

open access: yesAdvanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac   +7 more
wiley   +1 more source

Core Structure of gp41 from the HIV Envelope Glycoprotein

open access: yesCell, 1997
D. Chan, D. Fass, J. Berger, P. S. Kim
semanticscholar   +1 more source

Responsive Polyelectrolyte Brushes in Applications: Functions, Stimuli, and Design Considerations

open access: yesAdvanced Materials, EarlyView.
With advances in the synthesis of polyelectrolyte brushes, these coatings of surface‐grafted chains find uses in an increasing number of applications. This review summarizes three core aspects of these brushes: how they introduce functionality to surfaces; how external stimuli influence their properties; and what practical considerations should be ...
Leon A. Smook   +3 more
wiley   +1 more source

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