Results 231 to 240 of about 1,005,229 (334)

Recurrent Optic Neuritis With MRI-Negative Myelopathy in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD). [PDF]

Cureus
Harrilal-Maharaj K, Nevajda B.
europepmc   +1 more source

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source

Amaurosis Fugax Dolorosa: A Prodromal Syndrome in Optic Neuritis Associated With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. [PDF]

Neurol Neuroimmunol Neuroinflamm
Vilaseca A, Syc-Mazurek SB, Vorasoot N, Tajfirouz DA, Eggenberger E, Chodnicki KD, Pittock SJ, Chen JJ, Flanagan EP.   +8 more
europepmc   +1 more source

Nanomelic chondrocytes synthesize a glycoprotein related to chondroitin sulfate proteoglycan core protein.

, 1988
C. M. O'Donnell, K Kaczman-Daniel, Paul F. Goetinck, Barbara M. Vertel   +3 more
openalex   +1 more source

Platelet IκB Kinase-β Deficiency Increases Mouse Arterial Neointima Formation via Delayed Glycoprotein Ibα Shedding [PDF]

, 2012
Shujian Wei, Huan Wang, Guoying Zhang, Ying Lu, Xiaofei An, Shumei Ren, Yunmei Wang, Yuguo Chen, James G. White, Chunxiang Zhang, Daniel I. Simon, Chaodong Wu, Zhenyu Li, Yuqing Huo   +13 more
openalex   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Exploring the Activity of a Novel <i>N</i>-Glycosidase (EndoBI-2): Recombinant Production to Release Bioactive Glycans. [PDF]

Int J Mol Sci
Duman H, Avcı İ, Salih B, Kayılı HM, Bechelany M, Karav S.   +5 more
europepmc   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Molecular and Functional Insights into Thyrostimulin and Its Subunits-GPA2/GPB5. [PDF]

Int J Mol Sci
Nakad N, Fares F.
europepmc   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source