Results 241 to 250 of about 111,765 (333)

Halofuginone Disrupted Collagen Deposition via mTOR‐eIF2α‐ATF4 Axis to Enhance Chemosensitivity in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
COL1A1, a major component of ECM, contributes to chemoresistance and poor prognosis in ovarian cancer. Halofuginone (HF) attenuates CAF‐secreted COL1A1 through mTOR‐eIF2α‐ATF4 axis. Notably, HF disrupts collagen deposition to form the looser ECM and facilitates CD8+ T cell infiltration, partially via M2‐M1 macrophage polarization to enhance ...
Wenxin Li   +8 more
wiley   +1 more source

Distinct spatio-temporal Ca2+ signaling elicited by integrin α2β1 and glycoprotein VI under flow [PDF]

open access: bronze, 2009
M. Mazzucato   +8 more
openalex   +1 more source

Galectin‐9 activates platelet ITAM receptors glycoprotein VI and C‐type lectin‐like receptor‐2 [PDF]

open access: hybrid, 2021
Zhaogong Zhi   +11 more
openalex   +1 more source

Exciton‐Photon Coupling Microcavity as a Selective Biosensing Platform for Nonlocal Terahertz Metamaterials

open access: yesAdvanced Science, EarlyView.
The nonlocal metamaterial, characterized by strong light‐matter coupling, can be integrated with functionalized colloidal gold and monoclonal tag antibodies to enable rapid multidimensional detection and identification of total prostate‐specific antigen in complex environmental solutions.
Guifang Wu   +10 more
wiley   +1 more source

Silk Fibroin Nanoparticles for Enhanced Cuproptosis and Immunotherapy in Pancreatic Cancer Treatment

open access: yesAdvanced Science, EarlyView.
Cuproptosis can be triggered via intracellular copper overload mediated by elesclomol (ES).Enhancing ES‐Cu's tumor targeting and circulation stability can efficiently induce tumor cuproptosis. TSF@ES‐Cu protect ES‐Cu, target tumors via natural RGD sequences, and release through multi‐responsiveness.
Si Gao   +7 more
wiley   +1 more source

Expression of platelet glycoprotein VI is associated with transient ischemic attack and stroke [PDF]

open access: green, 2009
Boris Bigalke   +9 more
openalex   +1 more source

Fish Swim Bladder‐Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis

open access: yesAdvanced Science, EarlyView.
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu   +9 more
wiley   +1 more source

CO‐Releasing Polyoxometalates Nanozyme with Gut Mucosal Immunity and Microbiota Homeostasis Remodeling Effects for Restoring Intestinal Barrier Integrity

open access: yesAdvanced Science, EarlyView.
A CO‐releasing polyoxometalates nanozyme (PMC) is engineered by coordinating pentacarbonyl manganese bromide with molybdenum‐based polyoxometalates nanoclusters. PMC exhibits targeted accumulation at IBD sites, efficient ROS scavenging, and responsive CO release.
Hongyang Lu   +16 more
wiley   +1 more source

The humanized platelet glycoprotein VI Fab inhibitor EMA601 protects from arterial thrombosis and ischaemic stroke in mice. [PDF]

open access: yesEur Heart J
Navarro S   +9 more
europepmc   +1 more source

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