Results 261 to 270 of about 124,462 (290)
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Platelet Glycoprotein VI Contributes to Murine Experimental Metastasis
Blood, 2008Abstract A key receptor supporting the normal role of platelets in hemostasis and thrombosis is the collagen receptor, glycoprotein (GP)VI. GPVI is a member of the immunoglobulin super family and is uniquely expressed on the surface of platelets where it is assembled with the ITAM-bearing activation subunit, FcR-g.
Jerry Ware, Susan Russell, Shashank Jain
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Dimeric Glycoprotein VI Binds to Collagen but Not to Fibrin
Thrombosis and Haemostasis, 2018AbstractPlatelet glycoprotein VI (GPVI) acts as a decisive collagen receptor in atherothrombosis. Besides collagen, injured atherosclerotic plaques expose tissue factor (TF) that triggers fibrin formation. Two recent studies reported that platelet GPVI also functions as fibrin receptor, which would importantly widen the mode of action of GPVI-targeted ...
Ebrahim, Mariam +13 more
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Platelet Receptor Glycoprotein VI in Ischaemic Stroke
2020Platelet activation, thrombus growth and subsequent thromboembolism underpins the pathophysiology of ischaemic stroke. At sites of atherothrombotic plaque rupture, it is established that platelet surface receptor glycoprotein (GP) VI-dimer binds to exposed sub-endothelial collagen, initiating the signalling required to cause platelet activation.
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Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis
Thrombosis and Haemostasis, 2018AbstractSepsis triggers a complex series of pathophysiologic events involving inflammatory responses and coagulation abnormalities. While circulating blood platelets are well-characterized for their contributions to coagulation, increasingly platelet-dependent effects on inflammation are being recognized.
Ahmed, Asfari +9 more
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Platelet Glycoprotein VI: A Novel Marker for Acute Coronary Syndrome
Seminars in Thrombosis and Hemostasis, 2007The platelet collagen receptor glycoprotein (GP) VI is critical for the formation of arterial thrombosis. GPVI platelet surface expression was examined in patients with stable angina and in patients with acute coronary syndrome (ACS). Surface expression of platelet activation markers such as P-selectin, GPIbalpha, and platelet GPVI was determined by ...
Boris, Bigalke +4 more
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Plasma Soluble Glycoprotein VI: A Biomarker of Bleeding
Thrombosis and Haemostasis, 2023openaire +2 more sources
Humanized Glycoprotein VI Mouse to Study Anti-Glycoprotein VI Agents In Vivo
The Journal of Pharmacology and Experimental Therapeutics, 2012openaire +1 more source
Targeting Glycoprotein VI for Thromboembolic Disorders.
Arteriosclerosis, thrombosis, and vascular biology, 2020Frederik, Denorme, Matthew T, Rondina
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