Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks [PDF]
, 2017 Kristell Lebozec +4 more
openalex +1 more source
Contractility defects hinder glycoprotein VI-mediated platelet activation and affect platelet functions beyond clot contraction. [PDF]
Res Pract Thromb HaemostKenny M +10 more
europepmc +1 more source
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
American Journal of Hematology, EarlyView.ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source
Platelet Activation Through Membrane Glycoprotein VI
Japanese Journal of Thrombosis and Hemostasis, 1996 Kenzo Hirai +5 more
openaire +3 more sources
Aberrant glycosylation of osteopontin in a rat renal stone formation model: A preliminary study
, 2023 BJUI Compass, Volume 4, Issue 1, Page 63-65, January 2023.
Go Anan +5 more
wiley +1 more source
The CEACAM1-derived peptide QLSN impairs collagen-induced human platelet activation through glycoprotein VI [PDF]
, 2019 Yujia Ye +10 more
openalex +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey +6 more
wiley +1 more source
Molecular Cloning and Complete Nucleotide sequence of the Attenuated Rabies Virus SAD 819 [PDF]
, 1990 Conzelmann, Karl-Klaus +3 more
core
Antiviral effects and mechanism of Qi pi pill against influenza viruses
Animal Models and Experimental Medicine, EarlyView.Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang +10 more
wiley +1 more source
Animal models of human herpesvirus infection
Animal Models and Experimental Medicine, EarlyView.Human herpesvirus can infect humans and other vertebrates, primarily targeting the skin, mucous membranes, and neural tissues, thereby significantly impacting the health of both humans and animals. Animal models are crucial for studying virus pathogenesis, vaccine development, and drug testing.
Ziqing Jia +3 more
wiley +1 more source