Results 161 to 170 of about 210,654 (311)

Mass Spectrometry-Based Proteomics Methods for Systematic Identification and Quantification of Protein O-Glycosylation in Complex Biological Samples. [PDF]

J Am Soc Mass Spectrom
Fu L, Xu X, Wu R.
europepmc   +1 more source

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source

Glycosylation modulation as a therapeutic strategy for neuroinflammatory disorders: The potential of Tanshinone IIA. [PDF]

iScience
Li Y, Duan K, Liu G, Yan J, Wang Q, Zhang Y, Wang Y, Guo B, Zhang P, Zhang W, Kong D.   +10 more
europepmc   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Correction: Dual roles of Anisakis pegreffii proteins in macrophage immune dynamics

Frontiers in Immunology
Min-hao Zeng, Min-hao Zeng, Min-hao Zeng, Sarah Alsobaie, Xiao-xu Wang, Shan Li, Fahad M. Aldakheel, Mourad A. M. Aboul-Soud, Wei-bin Liu   +8 more
doaj   +1 more source

TMEM259/MEMBRALIN is a non-canonical ER-phagy receptor that associates with MAN1B1 and VCP to eliminate viral glycoproteins. [PDF]

Autophagy Rep
Camilleri JM, Zhang J, Wang T, Ahmad I, Li S, Zheng YH.   +5 more
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Polysialic Acid Synthesis on the <i>N</i>- and <i>O</i>‑Glycans of Salmonid Polysialyltransferase ST8Sia IV. [PDF]

ACS Omega
Seidel A, Decloquement M, Sun L, Vicogne D, Günther J, Galuska CE, Kallolimath S, Galuska SP, Harduin-Lepers A.   +8 more
europepmc   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

OLIGOSACCHARIDE REPROCESSING OF PLASMA MEMBRANE GLYCOPROTEINS

Plasma membrane glycoproteins of rat liver and cultured rat hepatocytes may undergo continuous reprocessing of their oligosaccharide units by de- and reglycosylation of terminal Sugars.
Tauber, R., Kreisel, W., Reutter, W.
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