Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source
Quantitative proteomic and glycoproteomic analysis identifies CLCA1, FBN1, and FGB as potential biomarkers for ulcerative colitis. [PDF]
Wang X +6 more
europepmc +1 more source
Stabilization of Glycoprotein Liquid Formulation Using Arginine: A Study with Lactoferrin as a Model Protein [PDF]
Hyun Jung Kim +2 more
openalex +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Cell membrane glycan contents are biochemical factors that constitute a kinetic barrier to viral particle uptake in a protein-nonspecific manner. [PDF]
Kaizuka Y, Machida R.
europepmc +1 more source
Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitors
Zhen Wang +8 more
openalex +1 more source
Molecular organization of prolactin granules. III. Intracellular transport of sulfated glycosaminoglycans and glycoproteins of the bovine prolactin granule matrix [PDF]
G. Giannattasio +5 more
openalex +1 more source
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Mass Spectrometry-Based Comparative Analysis of <i>N</i>-Glycosylation Alterations in Three Human Body Fluids in Parkinson's Disease. [PDF]
Zhao L +7 more
europepmc +1 more source

