Results 221 to 230 of about 393,899 (333)

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Site- and structure-specific characterization of glycoproteins of H11: potent vaccine candidates against parasitic worm <i>Haemonchus</i>. [PDF]

Front Immunol
Liu X, Liu F, Liu H, Ye L, Zhang Y, Peng W, Gupta N, Hu M, Wang C.   +8 more
europepmc   +1 more source

Glycoprotein [PDF]

, 2020
openaire   +1 more source

Multiple genes encode the major surface glycoprotein of Pneumocystis carinii.

, 1993
Joseph A. Kovacs, Frances E. Powell, Jeffrey C. Edman, Bettina Lundgren, Ariel F. Martinez, Brian G. Drew, Caroline Angus   +6 more
openalex   +1 more source

Analysis and nucleotide sequence of the genes encoding the surface‐layer glycoproteins of the hyperthermophilic methanogens Methanothermus fervidus and Methanothermus sociabilis [PDF]

, 1991
Günther Bröckl, Michael Behr, Stefan Fabry, Reinhard Hensel, H Kaudewitz, Elisabeth BIENDL, Helmut König   +6 more
openalex   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Comparative N‑glycoproteomics Characterization of N‑glycoproteins of H3N8 Viruses Produced in Chicken Embryos versus MDCK Cells. [PDF]

ACS Omega
Wang H, Zhang Z, Zhang X, Zhao L, Liu X, Ye Q, Tan WS.   +6 more
europepmc   +1 more source

The purification and properties of the lectin from potato tubers, a hydroxyproline-containing glycoprotein

, 1973
Anthony K. Allen, A. Neuberger
openalex   +2 more sources

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Quantitative proteomic and glycoproteomic analysis identifies CLCA1, FBN1, and FGB as potential biomarkers for ulcerative colitis. [PDF]

RSC Adv
Wang X, Bo S, Li Q, Li W, Xu L, Hu D, Yang S.   +6 more
europepmc   +1 more source