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Clinical Characteristics and Treatment Patterns of Hyperhidrosis in Northern Hokkaido: A Single-Center Retrospective Descriptive Study. [PDF]

J Dermatol
ABSTRACT Hyperhidrosis is a common condition associated with a substantial negative impact on the quality of life. Several studies have described the clinical characteristics and disease burden of patients with hyperhidrosis in Japan. However, comparable real‐world clinical data on hyperhidrosis from Hokkaido remain limited. We therefore evaluated real‐
Kishibe M, Noguchi A, Matsuya M, Matsumoto K, Igawa S, Fujita Y.   +5 more
europepmc   +2 more sources

Utilization Patterns of Nebulized Glycopyrronium in Patients Hospitalized for Acute Exacerbations of Obstructive Airway Disease (AEOAD)—Indian Expert Perspectives [PDF]

Advances in Respiratory Medicine
Background: Acute exacerbation of obstructive airway disease (AEOAD) is a major cause of hospitalization, morbidity, and premature mortality in India. Hospitalized patients for the same are predominantly treated with short-acting bronchodilators, which ...
Arjun Khanna, Pradyut Waghray, Ashok Kr Singh, Jinay Mehta, Rithik, Sagar Bhagat, Saiprasad Patil, Hanmant Barkate   +7 more
doaj   +2 more sources

Exploring the possibility of a predictable precision therapy of COPD with inclusion of glycopyrronium responsiveness: A real-world experience [PDF]

Lung India
Background: The advent of glycopyrronium responsiveness has opened the prospect of selective responsiveness-based prescription of bronchodilators-β2-agonists or anti-muscarinic agents (AMA) for COPD.
Parthasarathi Bhattacharyya, Shuvam Ghosh, Srijita Sen, Debkanya Dey, Sayoni Sengupta, Saayon Bej, Avishek Kar, Dipanjan Saha   +7 more
doaj   +2 more sources

Temporal and Partial Reversal of Airflow Limitation in Patients With COPD Treated With Single-Inhaler Long-Acting Dual Bronchodilators. [PDF]

Clin Respir J
Single‐inhaler dual bronchodilator therapy significantly improved FEV1, FEV1/FVC, and other spirometry parameters in patients with COPD. The improvements in FEV1 and FEV1/FVC exhibits different trends. Notably, 21 patients (11.5%) achieved a reversal of the FEV1/FVC ratio to over 70%.
Lu Y, Zhou Y, Xue L, Tian H, Han J, Yang Y, Guo Y, Jiang W, Chen C, Wang L, Song Y.   +10 more
europepmc   +2 more sources

Effects of glycopyrronium bromide versus anisodamine hydrobromide in preventing nausea and vomiting and relieving spasm after ERCP: a randomized controlled trial [PDF]

PeerJ
Background Postoperative nausea and vomiting (PONV) frequently occur in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) under general anesthesia.
Qingjing Ma, Dina Sun, Yan Rao, Yi Yang, Jie Liu, Chunmu Miao, Guangyou Duan, Guizhen Chen, Jie Chen   +8 more
doaj   +3 more sources

COPD and glycopyrronium responsiveness assessment: An appraisal

Lung India, 2023
Clinical Trial Registration: ECR/159/Inst/WB/2013/RR-20 Background: Glycopyrronium bromide (a long-acting antimuscarinic agent: LAMA) appears pharmacokinetically suitable for testing bronchodilator responsiveness as salbutamol (short-acting β2-agonist ...
Parthasarathi Bhattacharyya, Dipanjan Saha, Moumita Chatterjee, Sayoni Sengupta, Debkanya Dey, Rajat Banerjee   +5 more
doaj   +1 more source

Comparative efficacy and safety of glycopyrronium/formoterol fixed-dose combination versus glycopyrronium monotherapy in patients with moderate-to–severe COPD

Lung India, 2022
Background: The safety and efficacy of fixed-dose combination (FDC) of glycopyrronium bromide 12.5 μg/formoterol fumarate 12 μg (GB/FF) twice daily as dry powder inhalers (DPIs) compared to glycopyrronium 50 μg monotherapy (GLY) once daily as DPI in ...
Sundeep Salvi, Manish K Jain, Srikanth Krishnamurthy, Akash Balki, Rahul Kodgule, Monika Tandon, Sagar Bhagat, Sagar Panchal, Nishtha Khatri, Wen Wu, Amol Pendse, Saiprasad Patil, Hanmant Barkate   +12 more
doaj   +1 more source

Effects of long-acting muscarinic antagonists on promoting ciliary function in airway epithelium

BMC Pulmonary Medicine, 2022
Background Mucociliary clearance (MCC) is an essential defense mechanism in airway epithelia for removing pathogens from the respiratory tract. Impaired ciliary functions and MCC have been demonstrated in asthma and chronic obstructive pulmonary disease (
Mineo Katsumata, Tomoyuki Fujisawa, Yosuke Kamiya, Yuko Tanaka, Chiaki Kamiya, Yusuke Inoue, Hironao Hozumi, Masato Karayama, Yuzo Suzuki, Kazuki Furuhashi, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Masato Maekawa, Mitsutoshi Setou, Hiroshi Watanabe, Koji Ikegami, Takafumi Suda   +17 more
doaj   +1 more source

Efficacy of indacaterol/glycopyrronium versus salmeterol/fluticasone in current and ex-smokers: a pooled analysis of IGNITE trials

ERJ Open Research, 2021
Inhaled corticosteroids have proven to be less effective in asthmatic patients who smoke; however, there is limited information on the efficacy of inhaled corticosteroid-containing regimens in COPD patients who continue smoking.
David M.G. Halpin, Claus F. Vogelmeier, Karen Mezzi, Pritam Gupta, Konstantinos Kostikas, Jadwiga A. Wedzicha   +5 more
doaj   +1 more source

Feasibility of testing bronchodilator responsiveness with glycopyrronium in obstructive airway diseases: the initial appraisal of the pilot experience

The Journal of Association of Chest Physicians, 2021
Background: The short onset of action of glycopyrronium bromide, makes it a suitable antimuscarinic agent to test bronchodilator-responsiveness in airway diseases. The objective of the study was to explore the feasibility of the testing so.
Parthasarathi Bhattacharyya, Dipanjan Saha, Sayoni Sengupta, Debkanya De   +3 more
doaj   +1 more source