Results 51 to 60 of about 2,997 (148)

Economic evidence for licensed ready‐to‐administer intravenous products compared with standard vials and ampoules: a systematic review

Anaesthesia, Volume 81, Issue 6, Page 867-874, June 2026.
Summary Introduction Injectable medicines represent a significant proportion of the annual medicines expenditure of the NHS in England, totalling £7 billion ($9.4 billion, €8.0 billion) in 2023. This represents approximately 70% of hospital medicines spending and includes essential treatments delivered at the point of care, such as chemotherapy ...
Suzanne Al‐Rawi, Matthew Greening, Sue Ladds   +2 more
wiley   +1 more source

Combination therapy with indacaterol and glycopyrronium bromide in the management of COPD: an update on the evidence for efficacy and safety

Therapeutic Advances in Respiratory Disease, 2015
The international guidelines on chronic obstructive pulmonary disease (COPD) recommend inhaled bronchodilators for maintenance treatment of the disease. These drugs include β2-agonists and muscarinic antagonists, which are both available as short-acting ...
Erminia Ridolo, Marcello Montagni, Gian Galeazzo Riario-Sforza, Marco Baroni, Cristoforo Incorvaia   +4 more
doaj   +1 more source

The effect of glycopyrronium and indacaterol, as monotherapy and in combination, on the methacholine dose-response curve of mild asthmatics: a randomized three-way crossover study

Respiratory Research, 2017
Background Methacholine dose-response curves illustrate pharmacologic bronchoprotection against methacholine-induced airway hyperresponsiveness and can be used to quantitate changes in airway sensitivity (position), reactivity (slope), and maximal ...
Christianne M. Blais, Beth E. Davis, Donald W. Cockcroft   +2 more
doaj   +1 more source

2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot, Forbes D. Porter, Tatiana Bremova‐Ertl, Uma Ramaswami, Caroline Hastings, Bénédicte Héron, Justin Hopkin, Joella Melville, Hernan Amartino, Mireia del Toro, Federica Deodato, Fatih Ezgü, Paul Gissen, James B. Gibson, Can Ficicioglu, Roberto Giugliani, Orna Staretz‐Chacham, Frances Platt, Nathalie Guffon, Kristina Julich, Nikola Kresojević, Anna Lehman, Yann Nadjar, Susanne A. Schneider, Simon Jones, Eugen Mengel, Michel Tchan, Mark Walterfang, Ozlem Goker‐Alpan, Charlotte Dawson, Sandra Cowie, Toni Mathieson, Elizabeth Berry‐Kravis, Marc C. Patterson   +33 more
wiley   +1 more source

Effect of glycopyrronium on the phagocytosis of Streptococcus pneumoniae and Escherichia coli by macrophages and microglial cells

, 2021
Streptococcus pneumoniae and Escherichia coli are responsible for a wide variety of life-threatening infections such as pneumonia, sepsis, and meningitis.
Geisler, Elias Sándor
core   +1 more source

Translational Study Searching for Synergy between Glycopyrronium and Indacaterol

, 2014
We aimed to explore whether the acute bronchodilation induced by indacaterol 150 μg and glycopyrronium bromide 50 μg is additive or synergistic with respect to monocomponents by testing the type of effect ex vivo on isolated human bronchi and then in ...
Matera MG, Cazzola M, Calzetta, L, Matera, M, Calzetta L, Cazzola, M, Rogliani P, ROGLIANI, PAOLA, Segreti A, Segreti, A, Facciolo, F, CAZZOLA, MARIO, SEGRETI, ANDREA, Rogliani, P, Matera, MG, MATERA, Maria Gabriella, Facciolo F, Matera, M.   +17 more
core   +1 more source

Once-daily glycopyrronium bromide (Seebri Breezhaler(®)) for the treatment of chronic obstructive pulmonary disease (COPD)

, 2015
Introduction: Long-acting bronchodilators are the mainstay of pharmacological therapy for patients with chronic obstructive pulmonary disease (COPD). The choice of optimal bronchodilator therapy for COPD is increasingly difficult for clinicians as new ...
Ulrik, Charlotte Suppli
core   +1 more source

Explosive Weapons Trauma Care Collective (EXTRACCT) Blast Injury Clinical Practice Guideline: Ocular Trauma

World Journal of Surgery, Volume 50, Issue 2, Page 289-297, February 2026.
This clinical practice guideline from the Explosive Weapons Trauma Care Collective (EXTRACCT) group reviews current best practice for the management of ocular trauma in conflict‐affected regions, where explosive weapons are used and healthcare infrastructure is limited.
Emma Butterfield, Alistair Bolt, Gerry Clare, John Mattia, Aung Maw Tin‐U, Iddi Ndyabawe, Larry Schwab, Siegfried Karl Wagner, On behalf of the EXTRACCT Clinical Practice Guidelines Collaboration   +8 more
wiley   +1 more source

Relieving exertional dyspnea during the 3-min constant speed shuttle test in patients with COPD with indacaterol/glycopyrronium tiotropium: the RED trial

Therapeutic Advances in Respiratory Disease, 2020
Background: Exertional dyspnea is a cardinal feature of chronic obstructive pulmonary disease (COPD) and a major cause of activity limitation. Although dual bronchodilation is more effective than bronchodilator monotherapy at improving resting pulmonary ...
Jessie Beaulieu, Dennis Jensen, Denis E. O’Donnell, Cynthia Brouillard, Lauren Tracey, Sandra Vincent, Éric Nadreau, Emmanuelle Bernard, Sarah Bernard, François Maltais   +9 more
doaj   +1 more source

Development and Validation of the Japanese Version of the Hyperhidrosis Quality of Life Index

The Journal of Dermatology, Volume 53, Issue 2, Page 210-218, February 2026.
ABSTRACT Hyperhidrosis decreases an individual's quality of life (QOL). The Hyperhidrosis Quality of Life Index (HidroQoL) measures the impact of hyperhidrosis on QOL and has established reliability and validity. However, a Japanese version does not exist.
Sayaka Ogawa, Jun Tayama, Paul Kamudoni, Sam Salek, Peter Bernick, Masakazu Kobayashi, Seiko Nakamichi, Hiroyuki Murota   +7 more
wiley   +1 more source