Results 161 to 170 of about 151,431 (341)

THE CARDIOACTIVE METABOLITES OF DIGITALIS GLYCOSIDES

, 1956
Bradley T. Brown, Stephen E. Wright
openalex   +1 more source

Toward a Cannabis Terroir: Untargeted Metabolomic Profiling of Authentic Samples Using Gas Chromatography–High‐Resolution Mass Spectrometry (GC‐HRMS) and Liquid Chromatography–High‐Resolution Tandem Mass Spectrometry (LC‐HRMS/MS)

Drug Testing and Analysis, EarlyView.
This study developed a comprehensive metabolomics workflow using GC‐HRMS and LC‐HRMS/MS and analyzed 35 CBD‐type cannabis flowers grown under varying conditions. Key discriminative compounds enabled classification by chemical phenotype and cultivation environment. The results showed that environmental factors influence chemical profiles, supporting the
Sandra N. Poetzsch, Michael Poetzsch, Thomas Kraemer, Andrea E. Steuer   +3 more
wiley   +1 more source

DIGitoxin to Improve ouTcomes in patients with advanced chronic Heart Failure (DIGIT‐HF): Baseline characteristics compared to recent randomized controlled heart failure trials

European Journal of Heart Failure, EarlyView.
Effects of digitoxin compared to placebo on efficacy and safety in patients with heart failure and reduced ejection fraction (HFrEF). Primary endpoint: time to all‐cause death and first hospitalization for worsening heart failure (whatever occurs first). ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNI, angiotensin
Udo Bavendiek, Nele Henrike Thomas, Dominik Berliner, Xiaofei Liu, Johannes Schwab, Andreas Rieth, Lars S. Maier, Sven Schallhorn, Eleonora Angelini, Samira Soltani, Fabian Rathje, Mircea‐Andrei Sandu, Welf Geller, Thomas Gaspar, Rainer Hambrecht, Marija Zdravkovic, Sebastian Philipp, Dragana Kosevic, Georg Nickenig, Daniel Scheiber, Sebastian Winkler, Peter Moritz Becher, Philipp Lurz, Martin Hülsmann, Maria von Karpowitz, Christoph Schröder, Barbara Neuhaus, Anika Seltmann, Heiko von der Leyen, Christian Veltmann, Stefan Störk, Michael Böhm, Armin Koch, Anika Großhennig, Johann Bauersachs, on behalf of the DIGIT‐HF Study Group   +35 more
wiley   +1 more source

Contribution to the Chemistry and Pharmacology of the Digitalis Purpurea Glycosides

, 1948
Evan W. McChesney, Frederick C. Nachod, M.E. Auerbach, Fritz Laquer   +3 more
openalex   +1 more source

Redox‐Convertible Groups to Expand the Substrate Scope for Pentafluorosulfanylation of Styrenes by Photocatalytic Activation of Sulfur Hexafluoride

European Journal of Organic Chemistry, EarlyView.
The redox properties of the substrates must fit to the photoredox cycle for the activation of SF6. Strong electron‐donating groups turned α‐phenyl styrenes into a redox‐inactive state. These substrates are converted into redox‐active derivatives by reversible modifications of the critical substituents.
Sven Klehenz, Hannes Kucher, Hans‐Achim Wagenknecht   +2 more
wiley   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

Quantitative Colorimetric Method for some Cardio-Active Glycosides with 1, 3, 5-Trinitrobenzene

, 1951
Michiya Kimura
openalex   +2 more sources

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

A NOTE ON THE USE OF 1-BROMOTETRAMETHYLGLUCOSE FOR THE SYNTHESIS OF METHYLATED GLYCOSIDES

, 1932
P.A. Levene, Frank Cortese
openalex   +1 more source

Application of Bryophytes to Foods, Food Additives and Phytomedicines

Food Chemistry International, EarlyView.
Little attention has been paid to the bryophytes for use in the human diet, despite the presence of 23,000 species worldwide. (Marchantia polymorpha). ABSTRACT Little attention has been paid to the bryophytes for application on the human diet, despite the presence of 23,000 species worldwide.
Yoshinori Asakawa, Jianbo Xiao
wiley   +1 more source