Results 251 to 260 of about 254,661 (382)

Degradation strategies for structural characterization of insoluble synthetic polymers by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract With the advent of soft ionization techniques such as electrospray (ESI) and matrix‐assisted laser desorption/ionization (MALDI) to produce intact gas‐phase ions from nonvolatile macromolecules, mass spectrometry has become an essential technique in the field of polymeric materials.
Thierry N. J. Fouquet   +2 more
wiley   +1 more source

Oxidoreductive Cellulose Depolymerization by the Enzymes Cellobiose Dehydrogenase and Glycoside Hydrolase 61

open access: yesApplied and Environmental Microbiology, 2011
J. Langston   +5 more
semanticscholar   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

open access: yesMed Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang   +7 more
wiley   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

open access: yesNeuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng   +9 more
wiley   +1 more source

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