Results 41 to 50 of about 174,463 (312)
Nature Communications, 2018 Mechanism-based glycoside hydrolase inhibitors are carbohydrate analogs that mimic the natural substrate’s structure. Their covalent bond formation with the glycoside hydrolase makes these compounds excellent tools for chemical biology and potential drug
Weiwu Ren +13 more
semanticscholar +1 more source
Molecules, 2018 Monomeric and dimeric flavanol glycosides were analyzed in Vitis vinifera grapes and seeds during ripening. An analytical method using ultra-high performance liquid chromatography coupled with a triple quadrupole mass spectrometry (UHPLC-ESI-QQQ-MS/MS ...
Marie Zerbib +3 more
doaj +1 more source
Rhizoferrin Glycosylation in Rhizopus microsporus
Journal of Fungi, 2020 Rhizopus spp. are the most common etiological agents of mucormycosis, causing over 90% mortality in disseminated infections. The diagnosis relies on histopathology, culture, and/or polymerase chain reaction.
Anton Škríba +7 more
doaj +1 more source
Facile Synthesis of Saikosaponins
Molecules, 2021 Saikosaponin A (SSa) and D (SSd) are typical oleanane-type saponins featuring a unique 13,28-epoxy-ether moiety at D ring of the aglycones, which exhibit a wide range of biological and pharmacological activities.
Ziqiang Wang +4 more
doaj +1 more source
Science Advances, 2015 Therapeutic enzyme treatment disrupts Pseudomonas biofilms, potentiating antibiotics and ameliorating the innate immune system. Bacterial biofilms present a significant medical challenge because they are recalcitrant to current therapeutic regimes. A key
Perrin Baker +15 more
semanticscholar +1 more source
Angewandte Chemie, EarlyView.This study designs an anchor peptide‐based immobilization strategy to expand the application of Pickering emulsion to glycosyltransferases (GTs) for the first time, addressing low conversion challenge in aqueous solutions. The glycosylation Pickering emulsion achieved more than 90% conversion of natural product glycosides with high recyclability ...
Peng Zhang +5 more
wiley +2 more sources
Synthesis of Glycosides by Glycosynthases
Molecules, 2017 The many advances in glycoscience have more and more brought to light the crucial role of glycosides and glycoconjugates in biological processes. Their major influence on the functionality and stability of peptides, cell recognition, health and immunity ...
Marc R. Hayes, Jörg Pietruszka
doaj +1 more source
Glycoside Hydrolases across Environmental Microbial Communities
PLoS Comput. Biol., 2016 Across many environments microbial glycoside hydrolases support the enzymatic processing of carbohydrates, a critical function in many ecosystems. Little is known about how the microbial composition of a community and the potential for carbohydrate ...
Renaud Berlemont, A. Martiny
semanticscholar +1 more source
Micro‐ and Nano‐Bots for Infection Control
Advanced Materials, EarlyView.This review presents a strategic vision for integrating micro‐ and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on ...
Azin Rashidy Ahmady +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.Sialyl glycosides containing 4‐N‐derivatized sialic acids synthesized by a highly efficient one‐pot two‐enzyme (OP2E) chemoenzymatic sialylation strategy have been shown to be versatile probes. They can resist sialidase cleavage, be selective substrates by influenza sialidases, or be nanomolar substrate analog‐based inhibitors and affinity ligands ...
Yue Yuan +6 more
wiley +2 more sources