Results 61 to 70 of about 254,661 (382)

Design, Synthesis, and Antimicrobial Activities of 1,2,3-Triazole Glycoside Clickamers

open access: yesMolecules, 2020
Bacterial resistance remains a significant threat and a leading cause of death worldwide, despite massive attempts to control infections. In an effort to develop biologically active antibacterial and antifungal agents, six novel aryl-substituted-1,2,3 ...
Tamer El Malah   +4 more
doaj   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

open access: yesAdvanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Acylsulfonamide safety-catch linker : promise and limitations for solid-phase oligosaccharide synthesis [PDF]

open access: yes, 2012
Safety-catch linkers are useful for solid-phase oligosaccharide synthesis as they are orthogonal to many common protective groups. A new acylsulfonamide safety-catch linker was designed, synthesized and employed during glycosylations using an automated ...
Collot, M.   +3 more
core   +2 more sources

A Hydro‐Expansive and Degradable Biomaterial Enabling Shape Recovery of Film‐Based Devices in Biofluids

open access: yesAdvanced Materials, EarlyView.
A chitosan‐based bio‐composite exhibits stable and strong tensile strength during volumetric expansion in body fluids, serving as a functional coating that enables a thin film‐based device to self‐flatten from its tubular shape required for catheter delivery.
Ruoxing Wang   +11 more
wiley   +1 more source

Influence of Dielectric Environment upon Isotope Effects onGlycoside Heterolysis: Computational Evaluation and AtomicHessian Analysis [PDF]

open access: yes, 2019
Isotope effects depend upon the polarity of the bulk medium in which a chemical process occurs. Implicit solvent calculations with molecule-shaped cavities show that the equilibrium isotope effect (EIE) for heterolysis of the glycosidic bonds in 5 ...
Porter, Alexander J.   +3 more
core   +1 more source

Proteomic Analysis of a Novel Bacillus Jumbo Phage Revealing Glycoside Hydrolase As Structural Component

open access: yesFrontiers in Microbiology, 2016
Tailed phages with genomes of larger than 200 kbp are classified as Jumbo phages and exhibited extremely high uncharted diversity. The genomic annotation of Jumbo phage is often disappointing because most of the predicted proteins, including structural ...
Yihui Yuan, M. Gao
semanticscholar   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Pretreatment of citrus by-products affects polyphenol recovery:a review [PDF]

open access: yes, 2018
A large amount of citrus waste is generated annually. This waste is of great economic worth, since it contains high levels of polyphenols, which have attracted scientific interest due to their potent antimicrobial and antiradical activities. Pretreatment
Bowyer, Michael C.   +7 more
core   +1 more source

Discovery of Surface‐Induced Resonance Shift of 4‐Nitrophenol Enabling Direct Monitoring of an Enzymatic Reaction

open access: yesAdvanced Sensor Research, EarlyView.
A surface‐modified porous silica consisting of acetyl‐protected mannose residue and co‐precipitated urea compounds promotes a distinct resonance shift of 4‐nitrophenol under neutral conditions upon interaction, that is revealed by confocal Raman spectroscopy. The quinone‐type resonance structure is favored over the phenol‐type.
Ayano Nakamura   +5 more
wiley   +1 more source

Rhizoferrin Glycosylation in Rhizopus microsporus

open access: yesJournal of Fungi, 2020
Rhizopus spp. are the most common etiological agents of mucormycosis, causing over 90% mortality in disseminated infections. The diagnosis relies on histopathology, culture, and/or polymerase chain reaction.
Anton Škríba   +7 more
doaj   +1 more source

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