Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae)
A new bioactive sterol glycoside, 3β-O-(3',4'-di-O-acetyl-β-D-arabinopyranosyl)-25ξ-cholestane-3β,5α,6β,26-tetrol-26-acetate) (carijoside A, 1), was isolated from an octocoral identified as Carijoa sp.
Chih-Yang Liu+8 more
doaj +1 more source
RNA sampling and crystallographic refinement using Rappertk [PDF]
Background. Dramatic increases in RNA structural data have made it possible to recognize its conformational preferences much better than a decade ago. This has created an opportunity to use discrete restraint-based conformational sampling for modelling RNA and automating its crystallographic refinement. Results.
arxiv
Comparative study of the biological activities of the aqueous extracts of two spontaneous plants harvested in the Algerian Sahara [PDF]
The present study investigates the insecticidal and herbicidal effects of leaf extracts from two plants were harvested in the Northern Algerian Sahara. These are Cleome arabica (Capparaceae) and Pergularia tomentosa (Asclepiadaceae). The efficacy of the extracts from the plants was evaluated by the reflux extraction method.
arxiv
Evolution, substrate specificity and subfamily classification of glycoside hydrolase family 5 (GH5)
BackgroundThe large Glycoside Hydrolase family 5 (GH5) groups together a wide range of enzymes acting on β-linked oligo- and polysaccharides, and glycoconjugates from a large spectrum of organisms. The long and complex evolution of this family of enzymes
H. Aspeborg+4 more
semanticscholar +1 more source
A cytotoxic survey on 2‐amino‐1H‐imidazol based synthetic marine sponge alkaloid analogues
Abstract Here, we describe the synthesis and biologic activity evaluation of 20 novel synthetic marine sponge alkaloid analogues with 2‐amino‐1H‐imidazol (2‐AI) core. Cytotoxicity was tested on murine 4T1 breast cancer, A549 human lung cancer, and HL‐60 human myeloid leukemia cells by the resazurin assay.
Nikolett Gémes+10 more
wiley +1 more source
How homogeneous are the trehalose, maltose and sucrose water solutions ? An Insight from Molecular Dynamics simulations [PDF]
The structural properties resulting from the reciprocal influence between water and three well-known homologous disaccharides, namely trehalose, maltose and sucrose, in aqueous solutions have been investigated in the 4-66 wt % concentration range by means of molecular dynamics computer simulations. Hydration numbers clearly show that trehalose binds to
arxiv
Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors
Sweet and sticky: This review describes recent advances in the synthesis and application of homo‐and heterovalent glycan‐scaffolds as potential candidates for efficient bacteria lectin inhibition. To study and address the many complex molecular mechanisms involved in multivalent lectin binding events, novel glycoconjugate designs and fine‐tunable ...
Sandra Behren, Ulrika Westerlind
wiley +1 more source
Vasorelaxant and Antispasmodic Effects of Some Polyphenols and Glycoside in Rat Smooth Muscles
Objective: The present study was undertaken to investigate the effect of Luteolin, chlorogenic acid, amygdalin and tannic acid on vascular smooth muscle contractility.
Mudhir S. Shekha
doaj
Analysis of plant metabolomics data using identification‐free approaches
Abstract Plant metabolomes are structurally diverse. One of the most popular techniques for sampling this diversity is liquid chromatography–mass spectrometry (LC‐MS), which typically detects thousands of peaks from single organ extracts, many representing true metabolites.
Xinyu Yuan+2 more
wiley +1 more source
Nanophotonics and DNA: New approaches [PDF]
The aim of the present work is spectroscopic and thermodynamic study of DNA catalytic properties in the following processes: a) redox; b) formation of inter-strand cross-links; c) performing of photo-dynamic effects; d) nanoscale resonance radiationless electron excitation energy transfer.
arxiv