Results 81 to 90 of about 249,654 (337)

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

open access: yesChemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow   +2 more
wiley   +1 more source

Vasorelaxant and Antispasmodic Effects of Some Polyphenols and Glycoside in Rat Smooth Muscles

open access: yesScience Journal of University of Zakho, 2014
Objective: The present study was undertaken to investigate the effect of Luteolin, chlorogenic acid, amygdalin and tannic acid on vascular smooth muscle contractility.
Mudhir S. Shekha
doaj  

Evolution of Flavanol Glycosides during Red Grape Fermentation

open access: yesMolecules, 2018
Monomeric and dimeric flavanol glycosides were quantified by UHPLC-MRM in Syrah (SYR) and Grenache (GRE) grapes and in their corresponding wines for the first time.
Marie Zerbib   +4 more
doaj   +1 more source

Diverse Phytochemicals and Bioactivities in the Ancient Fruit and Modern Functional Food Pomegranate (Punica granatum). [PDF]

open access: yes, 2017
Having served as a symbolic fruit since ancient times, pomegranate (Punica granatum) has also gained considerable recognition as a functional food in the modern era. A large body of literature has linked pomegranate polyphenols, particularly anthocyanins
Tian, Li, Wu, Sheng
core   +2 more sources

Novel Bioactive Multifunctional Polyphenols: A Chemo‐Enzymatic Approach

open access: yesChemistry – A European Journal, EarlyView.
One‐step synthesis of complex alkyl oxystilbenin glucosides (6‐47% yield) in alcoholic medium. Switching to ter‐BuOH as solvent afforded δ‐Viniferin diglucoside, with high selectivity and high yield (> 90%), that can be upgraded by enzymatic esterification to alkyl δ‐Viniferin diglucosides.
Amandine L. Flourat   +8 more
wiley   +1 more source

Marine Carbohydrate-Based Compounds with Medicinal Properties

open access: yesMarine Drugs, 2018
The oceans harbor a great diversity of organisms, and have been recognized as an important source of new compounds with nutritional and therapeutic potential.
Ariana A. Vasconcelos, Vitor H. Pomin
doaj   +1 more source

Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. [PDF]

open access: yes, 2019
Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Chen, Xi   +2 more
core   +2 more sources

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

open access: yesChemistry – A European Journal, EarlyView.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret   +9 more
wiley   +1 more source

Sulfated Polyhydroxysteroid Glycosides from the Sea of Okhotsk Starfish Henricia leviuscula spiculifera and Potential Mechanisms for Their Observed Anti-Cancer Activity against Several Types of Human Cancer Cells

open access: yesMarine Drugs
Three new monosulfated polyhydroxysteroid glycosides, spiculiferosides A (1), B (2), and C (3), along with new related unsulfated monoglycoside, spiculiferoside D (4), were isolated from an ethanolic extract of the starfish Henricia leviuscula ...
Alla A. Kicha   +9 more
doaj   +1 more source

New triterpenic compounds from Swertia chirata

open access: yesAncient Science of Life, 2017
Aim: To study the Phytochemical constituents of dried aerial parts of Swertia chirata Linn (family Gentianaceae). Methods: The ethanolic extract of the aerial parts of plant S.
Sakshi Bajaj   +2 more
doaj   +1 more source

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