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Glycoside hydrolases and glycosyltransferases: families and functional modules

Current Opinion in Structural Biology, 2001
The past year has witnessed the expected increase in the number of solved structures of glycoside hydrolases and glycosyltransferases, and their constitutive modules. These structures show that, while glycoside hydrolases display an extraordinary variety of folds, glycosyltransferases and carbohydrate-binding modules appear to belong to a much smaller ...
Y, Bourne, B, Henrissat
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Structural and sequence-based classification of glycoside hydrolases

Current Opinion in Structural Biology, 1997
The diversity of oligo- and polysaccharides provides an abundance of biological roles for these carbohydrates. The enzymes hydrolysing these compounds, the glycoside hydrolases, therefore mediate a wealth of biological functions. Glycoside hydrolases fall into a number of sequence-based families.
Henrissat, Bernard, Davies, G.
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A GLYCOSIDE-HYDROLASE INHIBITOR IN TREATMENT OF DUMPING SYNDROME

The Lancet, 1979
BAY g 5421, a glycoside-hydrolase inhibitor, produced symptomatic improvement in ten patients with the dumping syndrome. 100 mg BAY g 5421, given before a 50 g sucrose meal, produced pronounced attenuation of both hyperglycaemic and hypoglycaemic phases of plasma glucose levels; and it greatly reduced the rise in plasma levels of gastric inhibitory ...
J C, McLoughlin   +2 more
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Cln5 is secreted and functions as a glycoside hydrolase in Dictyostelium

Cellular Signalling, 2018
Ceroid lipofuscinosis neuronal 5 (CLN5) is a member of a family of proteins that are linked to neuronal ceroid lipofuscinosis (NCL). This devastating neurological disorder, known commonly as Batten disease, affects all ages and ethnicities and is currently incurable. The precise function of CLN5, like many of the NCL proteins, remains to be elucidated.
Robert J. Huber   +1 more
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Catalytic strategies of glycoside hydrolases

2018
Glycoside hydrolases (GHs) are enzymes that catalyze the hydrolysis of the glycosidic bond between two carbohydrate residues or a carbohydrate unit linked to a non-carbohydrate aglycon unit. Despite years of research dedicated to GHs, there are still several mechanistic details, relevant for individual GH enzymes, that remain to be investigated.
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Immunization with Dextransucrases and Glycosidic Hydrolases

Journal of Dental Research, 1972
J A, Hayashi, I L, Shklair, A N, Bahn
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A Bacillus licheniformis Glycoside Hydrolase 43 Protein Is Recognized as a MAMP

International Journal of Molecular Sciences, 2022
Hongxia Liu
exaly  

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