Association of maternal diabetes/glycosuria and pre-pregnancy body mass index with offspring indicators of non-alcoholic fatty liver disease [PDF]
BMC Pediatrics, 2016 Background: Little is known about early life determinants of non-alcoholic fatty liver disease (NAFLD). We examined associations of maternal pregnancy diabetes/glycosuria and pre-pregnancy body mass index (BMI) with offspring markers of NAFLD and liver ...
Bm, Mark P Callaway +5 more
core +7 more sources
A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria [PDF]
eLifeThe kidneys facilitate energy conservation through reabsorption of nutrients including glucose. Almost all the filtered blood glucose is reabsorbed by the kidneys.
Tumininu S Faniyan +8 more
doaj +3 more sources
Glycosuria in primary glomerulopathies: prevalence and prognostic significance
Brazilian Journal of Nephrology, 2021 Introduction: Tubular damage is common in glomerular diseases (GD). Glycosuria is a marker of tubular dysfunction and may be used to detect tubular lesion and CKD progression.
Carolina Ormonde +4 more
doaj +3 more sources
Glycosuria Alters Uropathogenic Escherichia coli Global Gene Expression and Virulence
mSphere, 2022 Uropathogenic Escherichia coli (UPEC) is the principal etiology of more than half of urinary tract infections (UTI) in humans with diabetes mellitus. Epidemiological data and studies in mouse model of ascending UTI have elucidated various host factors ...
Md Jahirul Islam +4 more
doaj +2 more sources
Role of Glycosuria in SGLT2 Inhibitor–Induced Cardiorenal Protection: A Mechanistic Analysis of the CREDENCE Trial [PDF]
Diabetes, 2023 SGLT2 inhibitors have been shown to provide pronounced reductions in cardiorenal outcomes, including cardiovascular death, heart failure, and renal failure. The mechanisms underlying these benefits remain uncertain. We hypothesized that the effects could
Ele Ferrannini +6 more
openalex +2 more sources
A single dose of dapagliflozin, an SGLT-2 inhibitor, induces higher glycosuria in GCK- and HNF1A-MODY than in type 2 diabetes mellitus [PDF]
Endocrine, 2017 AimsSGLT2 inhibitors are a new class of oral hypoglycemic agents used in type 2 diabetes (T2DM). Their effectiveness in maturity onset diabetes of the young (MODY) is unknown.
Jerzy Hohendorff +12 more
openalex +2 more sources
Influence of Familial Renal Glycosuria Due to Mutations in the SLC5A2 Gene on Changes in Glucose Tolerance over Time. [PDF]
PLoS ONE, 2016 Familial renal glycosuria is an inherited disorder resulting in glucose excretion in the urine despite normal blood glucose concentrations. It is most commonly due to mutations in the SLC5A2 gene coding for the glucose transporter SGLT2 in the proximal ...
Emilia Ottosson-Laakso +6 more
doaj +2 more sources
Journal of Diabetes, 2022 Aims To present the clinical features of two rare cases with hereditary renal glycosuria and diabetes, explore their responses to sodium‐glucose cotransporter 2 (SGLT2) inhibitor, and summarize the reported solute carrier family 5 member 2 (SLC5A2 ...
Qian Ren +3 more
doaj +2 more sources
Non-diabetic glycosuria as a diagnostic clue for acute tubulointerstitial nephritis in patients with azotemia [PDF]
Renal Failure, 2020 Background Glycosuria is one of the manifestations of acute tubulointerstitial nephritis (ATIN), but may also be observed in other renal diseases. In this study, we investigated the value of non-diabetic glycosuria as a diagnostic clue for ATIN.
Taeyeon Lee, Won Seok Yang
doaj +2 more sources
Nephropathic Cystinosis Presenting as Renal Fanconi Syndrome without Glycosuria [PDF]
Journal of Clinical and Diagnostic Research, 2015 Renal Fanconi syndrome is diagnosed by its cardinal features of glycosuria without diabetes, aminoaciduria, phosphaturia, and renal tubular acidosis. It is often associated with hypokalaemia, hypophosphatemia and rickets.
Jayashree Kanthila +2 more
doaj +2 more sources