Results 101 to 110 of about 29,612 (275)

PIK3R1 mutations in individuals with insulin resistance or growth retardation: Case series and in silico functional analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
We present a report on SHORT syndrome caused by PIK3R1 mutations, including findings from in silico analysis. Our results demonstrate that these mutations impair the ability of p85α to interact with phosphopeptides. ABSTRACT Aims/Introduction Phosphatidylinositol 3‐kinase (PI3K) plays a key role in insulin signaling, and mutations in PIK3R1, which ...
Tomofumi Takayoshi   +15 more
wiley   +1 more source

Screening for proteinuria and glycosuria among dental patients in Benin City

open access: yesNigerian Dental Journal, 2010
Objective: To screen for the presence of proteinuria and glycosuria amongst patients attending for routine care in a dental clinic in Benin- City, Edo State, Nigeria.
O. N. Obuekwe   +4 more
doaj   +1 more source

RENAL GLYCOSURIA [PDF]

open access: yesArchives of Internal Medicine, 1920
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openaire   +2 more sources

Dual ETA‐ETB receptor antagonism improves metabolic syndrome‐induced heart failure with preserved ejection fraction

open access: yesFundamental &Clinical Pharmacology, Volume 39, Issue 3, June 2025.
Abstract Background Metabolic syndrome (MetS) is a multifaceted disease associated with heart failure (HF), which affects the vascular system. The endothelin (ET) system is a key player in MetS and HF; therefore, targets for ET receptors are of therapeutic interest.
Francesca Lockwood   +11 more
wiley   +1 more source

Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice [PDF]

open access: yes, 2008
Hydrogen sulphide (H2S) has been involved in cardiovascular homoeostasis but data about its role in animal models of diabetic pathology are still lacking.
Brancaleone V   +5 more
core   +1 more source

Effect of Combined Leaf Extracts of Vernonia amygdalina (Bitter Leaf) and Gongronema latifolium (Utazi) on the Pancreatic beta-Cells of Streptozotocin- Induced Diabetic Rats [PDF]

open access: yes, 2011
The study evaluated the effect of combined extracts of Vernonia amygdalina (VA) and Gongronema latifolium (GL) on the pancreas of streptozotocin (STZ) induced diabetic Wistar rats. Thirty-two (32) albino rats were divided equally into 4 groups.
Akpantah, Amabe   +5 more
core   +1 more source

Elevation of the renal threshold for glucose is associated with insulin resistance and higher glycated hemoglobin levels

open access: yesJournal of Diabetes Investigation, 2020
Aims/Introduction The renal threshold for glucose (RTg) corresponds to a blood glucose level of ~180 mg/dL; however, in hospitals, patients are often encountered who are hyperglycemic, but urine glucose test strip‐negative, who remain negative for urine ...
Kunio Hieshima   +10 more
doaj   +1 more source

Body Mass Index and Urinalysis Markers in the Seemingly Healthy Young Adults

open access: yesFolia Medica Indonesiana, 2020
Higher prevalence of albuminuria, glycosuria, and haematuria was reported in the obese people than control. We aimed to analyze the BMI and urinalysis markers among the university students aged 18-21 years old in the IIKBW, Kediri to study any ...
Krisnawan Andy Pradana   +2 more
doaj   +1 more source

Factors associated with DPP4i or SGLT2i utilisation: a retrospective cohort study among people with type 2 diabetes mellitus

open access: yesJournal of Pharmacy Practice and Research, Volume 55, Issue 2, Page 117-128, April 2025.
Abstract Background Dipeptidyl peptidase‐4 inhibitors (DPP4i) and sodium‐glucose co‐transporter 2 inhibitors (SGLT2i) are increasingly used as glucose‐lowering therapies in Malaysia. Aim To examine factors associated with the initiation of DPP4i or SGLT2i among people with type 2 diabetes mellitus (T2DM) in Malaysia. Method A retrospective cohort study
Ruth Sim   +5 more
wiley   +1 more source

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