Results 111 to 120 of about 30,439 (285)

A Proof‐of‐Concept Phase 2a Partly Randomised Study Evaluating Leronlimab in Patients With Presumed Non‐Cirrhotic Metabolic Dysfunction–Associated Steatohepatitis

open access: yesLiver International Communications, Volume 6, Issue 4, December 2025.
ABSTRACT Chemokine receptor type 5 (CCR5) is upregulated in the livers of patients with metabolic dysfunction–associated steatohepatitis (MASH). Leronlimab, a humanised IgG4κ monoclonal antibody, directly binds the extracellular domains of CCR5, modulates downstream signalling and potentially can slow, reverse or prevent fibrosis. The aim of this study
Melissa Palmer   +10 more
wiley   +1 more source

Diabetes mellitus in children the role of pediatrician in the identification, follow-up and prevention. The role of pediatrician in the identification, follow-up and prevention

open access: yesМедицинский совет, 2015
The article presents the current criteria for the diagnosis of diabetes mellitus (DM), classification, clinical symptoms of hyperglycemia, pediatrician's tactics in detecting hyperglycemia and glycosuria.
A. V. Vitebskaya
doaj   +1 more source

Approach to renal glycosuria in children: a case report [PDF]

open access: yes, 2014
Introduction: The accidental finding of glycosuria should lead to the exclusion of diabetes mellitus. In the absence of hyperglycemia, glycosuria is probably of renal origin.
Amaral, Rosário   +4 more
core  

Blockade of cannabinoid CB1 receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 21, Page 5355-5377, November 2025.
Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau   +20 more
wiley   +1 more source

THE RELATIONS OF THE THYROID GLANDS TO GLYCOSURIA

open access: yesJournal of Experimental Medicine, 1909
1. After thyroidectomy the glycosuria, produced by ether or adrenalin in the normal animal, is greatly reduced. 2. Thyroidless dogs fed on powdered thyroid glands show a return of glycosuria more or less proportional to the amount ingested when treated ...
E. Grey, W. T. de Sautelle
semanticscholar   +1 more source

Efficacy and safety of pioglitazone, empagliflozin and glimepiride as third‐line agents in patients with type 2 diabetes inadequately controlled with metformin and DPP‐4 inhibitors: A multicentre, phase 4 randomized controlled trial

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 11, Page 6375-6385, November 2025.
Abstract Aims To assess the efficacy and safety of three triple‐combination therapies in patients with type 2 diabetes (T2D) inadequately controlled on metformin and a dipeptidyl peptidase‐4 (DPP‐4) inhibitor. Materials and methods This multicentre, prospective, randomised, open‐label, parallel‐group, phase 4 study included patients with T2D ...
Yun Kyung Cho   +10 more
wiley   +1 more source

RENAL GLYCOSURIA [PDF]

open access: yesArchives of Internal Medicine, 1920
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openaire   +1 more source

Effects of Exercise in Children and Adolescent with Type 1 Diabetes Mellitus [PDF]

open access: yes, 2015
Exercise is one of the most important components, together with insulin therapy and diet, in the clinical management of type 1 diabetes mellitus (T1DM).
Bonetti, Annalisa   +3 more
core   +1 more source

Neuroleptic Malignant Syndrome: A Case Report of the Oldest Man in Literature

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
Radiographic findings in a 96 year old‐man with neuroleptic malignant syndrome highlights the importance of early recognition and attention to systemic complications. ABSTRACT A diagnosis of neuroleptic malignant syndrome (NMS) was made in a 96‐year‐old man, representing the oldest documented case in the existing medical literature.
Forouzan Elyasi   +4 more
wiley   +1 more source

Diabetic mouse angiopathy is linked to progressive sympathetic receptor deletion coupled to an enhanced caveolin-1 expression. [PDF]

open access: yes, 2004
OBJECTIVE: Clinical studies have demonstrated that hyperglycaemia represents a major risk factor in the development of the endothelial impairment in diabetes, which is the first step in vascular dysfunction.
Brancaleone, Vincenzo   +10 more
core   +1 more source

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