Results 41 to 50 of about 22,701 (163)
Renal glucose handling in diabetes and sodium glucose cotransporter 2 inhibition
Indian Journal of Endocrinology and Metabolism, 2013 The kidneys play a major role in glucose homeostasis through its utilization, gluconeogenesis, and reabsorption via sodium glucose cotransporters (SGLTs).
Resham Raj Poudel
doaj +1 more source
Prolonged ketosis and glycosuria secondary to SGLT2 inhibitor therapy
Clinical Case Reports, 2021 Clinicians should be aware of the potential for the pharmacologic activity of SGLT2 inhibitors to persist long after the standard drug clearance period of five half‐lives, the typical duration used to guide pre‐operative medication recommendations.
David Bobrowski +3 more
doaj +1 more source
Monitoring of diabetic dogs [PDF]
, 2012 Diabetes mellitus is one of the most common endocrine disorders in the dog. Although diagnostics are relatively straightforward, treatment and especially adequate long-term monitoring are challenging.
Daminet, Sylvie +4 more
core
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Approach to renal glycosuria in children: a case report [PDF]
, 2014 Introduction: The accidental finding of glycosuria should lead to the exclusion of diabetes mellitus. In the absence of hyperglycemia, glycosuria is probably of renal origin.
Amaral, Rosário +4 more
core
ESC Heart Failure, EarlyView.Abstract Aims We aim to assess the efficacy of congestion relief and safety associated with adding SGLT2i (viz., dapagliflozin 10 mg) to intravenous loop diuretics within 24 h of hospital presentation in patients with acute heart failure (AHF). Methods and results A single‐centre open‐label clinical research study enrolled 98 patients admitted with an ...
Daniela Mocan +7 more
wiley +1 more source
Glycosuria and Acute Kidney Injury: A Rare Presentation of Acute Interstitial Nephritis
Kidney Medicine, 2020 Acute interstitial nephritis (AIN) is often induced by drugs and is a common cause of acute kidney injury. Clinically diagnosing AIN can often be challenging because these signs and symptoms rarely present in concert.
Benjamin A. Schwartz, Jason M. Kidd
doaj
Indian Journal of Endocrinology and Metabolism, 2017 Diabetes prevalence shows a continuous increasing trend in South Asia. Although well-established treatment modalities exist for type 2 diabetes mellitus (T2DM) management, they are limited by their side effect profile.
Sanjay Kalra +21 more
doaj +1 more source
An emerging protagonist: Sodium Glucose Co-transporters (SGLTs) as a burgeoning target for the treatment of diabetes mellitus [PDF]
, 2012 Contemporary therapies to rationalize the hyperglycaemia in type 2 diabetes mellitus (T2DM) generally involve insulin-dependent mechanisms and lose their effectiveness as pancreatic b-cell function decreases to a greater extent. The kidney emerges out as
Danish Ahmed +3 more
core +2 more sources
European Journal of Heart Failure, EarlyView.Myocardial ketone body oxidation contributes to empagliflozin‐induced improvements in cardiac contractility. Abstract Aims Sodium–glucose cotransporter 2 inhibitors (SGLT2i) improve cardiac performance and clinical outcomes in patients with heart failure, yet mechanisms underlying these beneficial effects remain incompletely understood.
Suzanne Nathalie Voorrips +11 more
wiley +1 more source