Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Water and Sodium Metabolism
Sodium-glucose cotransporter 2 (SGLT2) inhibitors exert hypoglycemic and diuretic effects by inhibiting the absorption of sodium and glucose from the proximal tubule.
Jun Tang +9 more
doaj +1 more source
We reported previously that overexpression of heterogeneous nuclear ribonucleoprotein F (Hnrnpf) in renal proximal tubular cells (RPTCs) suppresses angiotensinogen (Agt) expression, and attenuates systemic hypertension and renal injury in diabetic Hnrnpf-
Chao-Sheng Lo +9 more
semanticscholar +1 more source
Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Raised cortisol excretion rate in urine and contamination by topical steroids [PDF]
No abstract ...
Davies, D.L. +5 more
core +1 more source
Heart failure is common in diabetic cats : findings from a retrospective case-controlled study in first-opinionpractice [PDF]
Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Blue Skies Research Grant - RCVS Trust (Funder) +2 more
core +1 more source
Several studies have demonstrated that renal glucose reabsorption is increased in patients with type 2 diabetes. However, the increased renal glucose reabsorption may contribute to the progression of hyperglycemia.
Juan Chen +4 more
doaj +1 more source
Case Report: Multisystem inflammatory syndrome in children with associated proximal tubular injury
IntroductionSARS-CoV-2 infection in the pediatric population can be associated with a multiorgan inflammatory syndrome called children’s multisystem inflammatory syndrome (MIS-C).
Silvia Maria Orsi +20 more
doaj +1 more source
Cohort profile: the avon longitudinal study of parents and children: ALSPAC mothers cohort [PDF]
The Avon Longitudinal Study of Children and Parents (ALSPAC) was established to understand how genetic and environmental characteristics influence health and development in parents and children.
A. Boyd +50 more
core +2 more sources
Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes [PDF]
Background Despite the number of medications for type 2 diabetes, many people with the condition do not achieve good glycaemic control. Some existing glucose-lowering agents have adverse effects such as weight gain or hypoglycaemia. Type 2 diabetes tends
Clar, C. +3 more
core +1 more source
ACE-inhibition ameliorates vascular reactivity and delays diabetes outcome in NODmice. [PDF]
Recently, we have demonstrated a direct correlation among hyperglycaemia, vascular dysfunction and eNOS post-translational regulation in non non-obese diabetic mice (NOD).
Brancaleone, V +6 more
core +1 more source

