Results 81 to 90 of about 22,701 (163)

Observations related to chronologic and gynecologic age in pregnant adolescents. [PDF]

, 1984
A low chronologic age (less than or equal to 15 years) and low gynecologic age (less than or equal to 2 years) have been considered factors that increase medical complications among adolescent pregnant women. Gynecologic age (GA) is defined in this study
Felice, ME, Hollingsworth, DR, James, M, Shragg, P   +3 more
core  

The role of zinc in renal pathological changes in diabetic status [PDF]

, 2015
Diabetes mellitus (DM) was the 8th leading cause of death in 2011, resulting in 1.4 million deaths worldwide. One of the complications of DM is chronic kidney disease, which accounts for nearly 44% of all new cases of kidney failure in the US in 2011 ...
Fernando, Julie, Zhou, Shaobo
core   +1 more source

PIK3R1 mutations in individuals with insulin resistance or growth retardation: Case series and in silico functional analysis

Journal of Diabetes Investigation, Volume 16, Issue 8, Page 1526-1534, August 2025.
We present a report on SHORT syndrome caused by PIK3R1 mutations, including findings from in silico analysis. Our results demonstrate that these mutations impair the ability of p85α to interact with phosphopeptides. ABSTRACT Aims/Introduction Phosphatidylinositol 3‐kinase (PI3K) plays a key role in insulin signaling, and mutations in PIK3R1, which ...
Tomofumi Takayoshi, Yushi Hirota, Aki Sugano, Kenji Sugawara, Takehito Takeuchi, Mika Ohta, Kai Yoshimura, Seiji Nishikage, Akane Yamamoto, Yu Mimura, Shinji Higuchi, Jun Mori, Rie Kawakita, Tohru Yorifuji, Yutaka Takaoka, Wataru Ogawa   +15 more
wiley   +1 more source

Long-term renal outcome in children with OCRL mutations: retrospective analysis of a large international cohort [PDF]

, 2016
BACKGROUND: Lowe syndrome (LS) and Dent-2 disease (DD2) are disorders associated with mutations in the OCRL gene and characterized by progressive chronic kidney disease (CKD).
Addis, M, Ahn, YH, Anglani, F, Baronio, F, Bockenhauer, D, Bökenkamp, A, Bürger, J, Cheong, HI, Chung, WY, Fonduli, P, Gellermann, J, Gucev, Z, Konrad, M, Kołbuc, M, Krzemień, A, La Manna, A, La Scola, C, Lee, JW, Ludwig, M, Miklaszewska, M, Moczko, J, Niemirska, A, Paglialonga, F, Paripovic, D, Park, SJ, Park, YH, Rogowska-Kalisz, A, Roszak, M, Runowski, D, Rus, R, Said-Conti, V, Sartz, L, Sikora, P, Siteń, G, Stefanidis, CJ, Szczepańska, M, Tasic, V, Wasilewska, A, Zampetoglou, A, Zaniew, M, Załuska-Leśniewska, I, Zurrida, F   +41 more
core   +1 more source

Secondary Erythrocytosis Among Type 2 Diabetes Mellitus Patients With Hypogonadism Using Sodium‐Glucose Cotransporter 2 Inhibitors and Testosterone Replacement Therapy

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 4, July 2025.
Given the frequent association between T2DM and the wide availability and administration of SGLT‐2i as a novel anti‐diabetic class on the one hand and hypogonadism with TRT on the other, concurrent administration may precipitate secondary erythrocytosis.
Maharan Kabha, Hadar Dana, Sameer Kassem, Yoram Dekel, Hilla Cohen, Adnan Zaina   +5 more
wiley   +1 more source

Education and screening for chronic kidney disease in Indian youth: pilot program results

International Journal of Nephrology and Renovascular Disease, 2017
Panduranga S Rao,1 Julie A Wright Nunes,1 Brenda W Gillespie,2 Rachel L Perlman,1 Rajan Ravichandran3 1Division of Nephrology, Department of Internal Medicine, University of Michigan Health System, 2Department of Biostatistics, School of Public Health ...
Rao PS, Wright Nunes JA, Gillespie BW, Perlman RL, Ravichandran R   +4 more
doaj  

An overview of insulin therapy for the non‐specialist

Diabetes, Obesity and Metabolism, Volume 27, Issue S5, Page 3-15, July 2025.
Abstract Nearly all health professionals, whatever their practice or speciality, now have contact with a significant number of insulin‐using people with diabetes. People with type 1 diabetes are nearly universally managed on more complex insulin regimens, increasingly with complex support technology, and with some understanding of the concepts ...
Philip D. Home
wiley   +1 more source

A review of the safety of sodium‐glucose co‐transporter‐2 inhibitors

Diabetes, Obesity and Metabolism, Volume 27, Issue 7, Page 3598-3606, July 2025.
Abstract The development of sodium‐glucose co‐transporter‐2 (SGLT2) inhibitors represents a major turning point in the effort to preserve kidney function and prevent cardiovascular events and heart failure hospitalisations in those at high risk. These agents have now transcended their original glucose‐lowering indication and provide a range of clinical
Daniel Vincent O'Hara, Meg J. Jardine
wiley   +1 more source

Delayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington's Disease. [PDF]

, 2016
BACKGROUND: Impairments in energy metabolism are implicated in Huntington's disease (HD) pathogenesis. Reduced levels of the mitochondrial enzyme succinate dehydrogenase (SDH), the main element of complex II, are observed post mortem in the brains of HD ...
Morton, A Jennifer, Skillings, Elizabeth A   +1 more
core  

Effect of various mineral additives on the state of excretory renal function and the level of glycemia in rats in experimental alloxan diabetes mellitus

Фармакокинетика и Фармакодинамика, 2018
On this study presents the results of the use of mineral additives salsamenteria of hypocol, selenopyran and Magne-Вб on alloxan model of diabetes in rats. A significant hypoglycemic effect of Magne B6 and selenopyran. It is revealed that all connections,
O. A. Nazarenko, O. A. Gromova
doaj   +1 more source