Results 1 to 10 of about 46,844 (170)

Separation of glycosyl diglycerides from phosphatides using silicic acid column chromatography

Journal of Lipid Research, 1965
A procedure has been developed for the separation of the glycosyl diglycerides from the phosphatides of Gram-positive bacteria on columns of silicic acid.
Marie L. Vorbeck, G.V. Marinetti
doaj   +2 more sources

Facile access to C-glycosyl amino acids and peptides via Ni-catalyzed reductive hydroglycosylation of alkynes

Nature Communications, 2021
C-Glycosyl peptides/proteins are metabolically stable mimics of the native glycopeptides/proteins of great therapeutic potential, but their chemical synthesis is challenging. Here, the authors report a protocol for the synthesis of vinyl C-glycosyl amino
Yan-Hua Liu, Yu-Nong Xia, Tayyab Gulzar, Bingcheng Wei, Haotian Li, Dapeng Zhu, Zhifei Hu, Peng Xu, Biao Yu   +8 more
doaj   +1 more source

Remote participation during glycosylation reactions of galactose building blocks: Direct evidence from cryogenic vibrational spectroscopy [PDF]

, 2020
The stereoselective formation of 1,2‐cis‐glycosidic bonds is challenging. However, 1,2‐cis‐selectivity can be induced by remote participation of C4 or C6 ester groups.
Gilmore, K., Greis, K., Helden, G., Kirschbaum, C., Marianski, M., Meijer, G., Moon, S., Mucha, E., Pagel, K., Pard, A., Seeberger, P., Thomas, D.   +11 more
core   +1 more source

Carbamate-Based Bolaamphiphile as Low-Molecular-Weight Hydrogelators

Gels, 2016
A new bolaamphiphile analog featuring carbamate moieties was synthesized in six steps starting from thymidine. The amphiphile structure exhibits nucleoside-sugar polar heads attached to a hydrophobic spacer via carbamate (urethane) functions.
Laurent Latxague, Alexandra Gaubert, David Maleville, Julie Baillet, Michael A. Ramin, Philippe Barthélémy   +5 more
doaj   +1 more source

Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes [PDF]

, 1997
Hen egg-white lysozyme has long been the paradigm for enzymatic glycosyl hydrolysis with retention of configuration, with a protonated carboxylic acid and a deprotonated carboxylate participating in general acid-base catalysis.
Blake C. C. F., C−, Davies G. J., Ford L. O., Henrissat B., Iseli B., Johnson L. N., Jones T. A., Kirby A., Knapp S., Kobayashi S., Koshland D. E., Perrakis A., Phillips D. C., Piszkiewicz D., Rao V. H., Rozeboom H. J., Sinnot M. L., Strynadka N. C. J., Sulzenbacher G., Terwisscha van Scheltinga A. C., Terwisscha van Scheltinga A. C., Terwisscha van Scheltinga A. C., Tews I., Thunnissen A. M. W. H., Tronrud D. E., van Roey P., Vårum K. M., Weaver L. H.   +28 more
core   +3 more sources

Glycosyl-Nucleolipids as New Bioinspired Amphiphiles

Molecules, 2013
Four new Glycosyl-NucleoLipid (GNL) analogs featuring either a single fluorocarbon or double hydrocarbon chains were synthesized in good yields from azido thymidine as starting material. Physicochemical studies (surface tension measurements, differential
Philippe Barthélémy, Eric Amigues, Amit Patwa, Laurent Latxague   +3 more
doaj   +1 more source

Stereoselective gold(I)-catalyzed approach to the synthesis of complex α-glycosyl phosphosaccharides

Nature Communications, 2022
Glycosyl phosphosaccharides represent a large and important family of complex glycans, but are difficult to synthesize efficiently. Here, the authors disclose a stereoselective methodology to make α-glycosyl phosphosaccharides, via gold(I)-catalyzed ...
Xiaojuan Zhang, Yutong Yang, Jiahao Ding, Yun Zhao, Hongbin Zhang, Yugen Zhu   +5 more
doaj   +1 more source

Trapping and Characterization of the Reaction Intermediate in Cyclodextrin Glycosyltransferase by Use of Activated Substrates and a Mutant Enzyme [PDF]

, 1997
Cyclodextrin glycosyltransferases (CGTases) catalyze the degradation of starch into linear or cyclic oligosaccharides via a glycosyl transfer reaction occurring with retention of anomeric configuration.
Dijkstra, Bauke W.,, He, Shouming,, Mosi, Renee,, Uitdehaag, Joost,, Withers, Stephen G.,   +4 more
core   +3 more sources

Intracellular glycosyl hydrolase PslG shapes bacterial cell fate, signaling, and the biofilm development of Pseudomonas aeruginosa

eLife, 2022
Biofilm formation is one of most important causes leading to persistent infections. Exopolysaccharides are usually a main component of biofilm matrix.
Jingchao Zhang, Huijun Wu, Di Wang, Lanxin Wang, Yifan Cui, Chenxi Zhang, Kun Zhao, Luyan Ma   +7 more
doaj   +1 more source

Metal-free glycosylation with glycosyl fluorides in liquid SO2

Beilstein Journal of Organic Chemistry, 2021
Liquid SO2 is a polar solvent that dissolves both covalent and ionic compounds. Sulfur dioxide possesses also Lewis acid properties, including the ability to covalently bind Lewis basic fluoride ions in a relatively stable fluorosulfite anion (FSO2 ...
Krista Gulbe, Jevgeņija Lugiņina, Edijs Jansons, Artis Kinens, Māris Turks   +4 more
doaj   +1 more source