Results 191 to 200 of about 81,861 (342)

A general language model for peptide identification [PDF]

arXiv
Advances in peptide identification are revolutionizing our ability to decipher protein functions and accelerate therapeutic discovery. We present PDeepPP, a deep learning framework that integrates pretrained protein language models with parallel transformer-CNN architectures, achieving state-of-the-art performance in peptide characterization tasks. The
arxiv  

Electrostatic potential as a reactivity scoring function in computer‐assisted enzyme engineering

The FEBS Journal, EarlyView.
We present a computational metric that quantifies the electrostatic complementarity of enzymes to the charge distribution of substrates at the transition state. Implemented in BindScan, this metric accurately predicts functionally relevant mutations in glycoside hydrolases.
Aitor Vega, Antoni Planas, Xevi Biarnés
wiley   +1 more source

Foundation model for mass spectrometry proteomics [PDF]

arXiv
Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrumentation and resulting data, sophisticated computational methods are required for the processing and interpretation of acquired mass spectra.
arxiv  

Glycosyl ureides in ruminant nutrition [PDF]

, 1982
R. J. Merry, R. H. Smith, A. B. McAllan
openalex   +1 more source

The PNH French Working Group Experience: Building a Strong Network of Cytometrists

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon, Magali Le Garff‐Tavernier, Rémi Lestestu, Bernard Drenou, Agathe Debliquis, the PNH French Working Group «CytHem‐HPN», Chantal Fossat, Claire Loosen, Bernard Chatelain, Marie Loosveld   +9 more
wiley   +1 more source

Reaction of nucleophilic reagents with D-glycosyl- and D-gluconyl isothiocyanates.

, 1979
Hiroshi Takahashi, Noriyuki Nimura, Haruo Ogura   +2 more
openalex   +2 more sources

Antibodies to 5'-nucleotidase (CD73), a glycosyl-phosphatidylinositol-anchored protein, cause human peripheral blood T cells to proliferate. [PDF]

, 1989
Linda F. Thompson, J M Ruedi, Alison A. Glass, M G Low, Alexander H. Lucas   +4 more
openalex   +1 more source

DSD1/ZmICEb regulates stomatal development and drought tolerance in maize

Journal of Integrative Plant Biology, EarlyView.
DECREASED STOMATAL DENSITY 1/INDUCER OF CBF EXPRESSION b regulates maize stomatal development and drought tolerance, providing a promising target for the genetic improvement of drought tolerance in maize by manipulating stomatal density. ABSTRACT Maize (Zea mays L.) growth and yield are severely limited by drought stress worldwide. Stomata play crucial
Wenqi Zhou, Jun Yin, Yuqian Zhou, Yongsheng Li, Haijun He, Yanzhong Yang, Xiaojuan Wang, Xiaorong Lian, Xiaoyun Dong, Zengke Ma, Liang Chen, Suiwen Hou   +11 more
wiley   +1 more source

8-Alkylaminoadenyl nucleotides as probes of dehydrogenase interactions with nucleotide analogs of different glycosyl conformation.

, 1976
F E Evans, Nathan O. Kaplan
openalex   +1 more source

OsPRK1/2/3‐mediated reactive oxygen species signaling is required for pollen tube germination in rice

Journal of Integrative Plant Biology, EarlyView.
The rice pollen‐specific receptor‐like kinases OsPRK1, OsPRK2, and OsPRK3 play a crucial role in reactive oxygen species (ROS)‐mediated pollen hydration and germination. Triple mutants display male sterility due to decreased ROS levels and impaired pollen hydration, and their germination phenotype can be partially restored by exogenous application of ...
Eui‐Jung Kim, Ye‐jin Son, Ji‐Hyun Kim, Woo‐Jong Hong, Su Kyoung Lee, Sun Tae Kim, Wanqi Liang, Sunok Moon, Yu‐Jin Kim, Ki‐Hong Jung   +9 more
wiley   +1 more source