Results 61 to 70 of about 81,861 (342)
Draft Genome Sequence of the Lignocellulose Decomposer Thermobifida fusca Strain TM51. [PDF]
, 2013 Here, we present the complete genome sequence of Thermobifida fusca strain TM51, which was isolated from the hot upper layer of a compost pile in Hungary. T.
Beki +14 more
core +1 more source
Structural Insights into the Substrate Recognition of Ginsenoside Glycosyltransferase Pq3‐O‐UGT2
Advanced Science, Volume 12, Issue 11, March 20, 2025.This work reveals the crystal structures of Pq3‐O‐UGT2 with its substrates (Rh2 or F2), unveiling an Nα5‐oriented binding pocket and unique linker conformation. Hydrophobic interactions are crucial for substrate recognition, while hydrogen bonds enhance specificity for F2. This study enhances the understanding of ginsenoside UGTs' substrate recognition
Qiushuang Ji +13 more
wiley +1 more source
Glycosylated Notch and Cancer [PDF]
Frontiers in Oncology, 2016 Glycosylation is one of the key components influencing several signaling pathways implicated in cell survival and growth. The Notch signaling pathway plays a pivotal role in numerous cell fate specifications during metazoan development. Both Notch and its ligands are repeatedly glycosylated by the addition of sugar moieties, such as O-fucose, O-glucose,
Shanmugasundaram ePakkiriswami +4 more
openaire +5 more sources
Therapeutic Potential of Glycosyl Flavonoids as Anti-Coronaviral Agents
Pharmaceuticals, 2021 The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread all over the world, creating a devastating socio-economic impact.
Patrícia I. C. Godinho +2 more
doaj +1 more source
Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases. [PDF]
, 2015 MutY adenine glycosylases prevent DNA mutations by excising adenine from promutagenic 8-oxo-7,8-dihydroguanine (OG):A mismatches. Here, we describe structural features of the MutY active site bound to an azaribose transition state analog which indicate a
Cao, Sheng +6 more
core +2 more sources
Advanced Science, EarlyView.ProteoSeeker is a new metagenomic analysis tool that accelerates protein discovery. By automating key steps, it reduces computational complexity and enables comprehensive dataset analysis, performing protein identification, screening based on user‐defined protein families, and taxonomic analysis.
Georgios Filis +6 more
wiley +1 more source
Functional, pathogenic, and pharmacological roles of protein folding intermediates
Proteins: Structure, Function, and Bioinformatics, EarlyView., 2023 Abstract Protein expression and function in eukaryotic cells are tightly harmonized processes modulated by the combination of different layers of regulation, including transcription, processing, stability, and translation of messenger RNA, as well as assembly, maturation, sorting, recycling, and degradation of polypeptides.
Emiliano Biasini, Pietro Faccioli
wiley +1 more source
Identification and analysis of seven effector protein families with different adaptive and evolutionary histories in plant-associated members of the Xanthomonadaceae. [PDF]
, 2017 The Xanthomonadaceae family consists of species of non-pathogenic and pathogenic γ-proteobacteria that infect different hosts, including humans and plants.
Almeida, Nalvo F +14 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2017 The glycosylation of O-glycosyl trichloroacetimidate donors using a synergistic catalytic system of electron-deficient pyridinium salts/aryl thiourea derivatives at room temperature is demonstrated. The acidity of the adduct formed by the 1,2-addition of
Mukta Shaw +3 more
doaj +1 more source
Polysaccharide conformations measured by solution state x-ray scattering [PDF]
, 2019 Polysaccharides are semi-flexible polymers composed of sugar residues with a myriad of important functions including structural support, energy storage and immunogenicity. The local conformation of such chains is a crucial factor governing their interactions, where the relative orientation of adjacent sugar rings determines the propensity for hydrogen ...
arxiv +1 more source