PhyloTransformer: A Discriminative Model for Mutation Prediction Based on a Multi-head Self-attention Mechanism [PDF]
arXiv, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an ongoing pandemic infecting 219 million people as of 10/19/21, with a 3.6% mortality rate. Natural selection can generate favorable mutations with improved fitness advantages; however, the identified coronaviruses may be the tip of the iceberg, and potentially more fatal variants
arxiv
Animal Research and One Health, EarlyView.Brucellosis is a zoonotic disease caused by Brucella spp. which seriously jeopardize the health and safety of animals and human beings. In this study, a genetically stable Brucella rough RA343 strain was obtained by cross‐induction. The virulence and protective efficacy of RA343 were subsequently assessed. Overall, the RA343 strain is a promising novel
Linjiao Li +12 more
wiley +1 more source
Glycosylation with Glycosyl p-Bromophenyl Phthalates as New Efficient Glycosyl Donors
Bulletin of the Korean Chemical Society, 2005 AbstractFor Abstract see ChemInform Abstract in Full Text.
Soon Young Kwon +3 more
openaire +4 more sources
Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4
Beilstein Journal of Organic Chemistry, 2014 The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates ...
Pintu Kumar Mandal
doaj +1 more source
Total syntheses of conformationally-locked difluorinated pentopyranose analogues and a pentopyranosyl phosphate mimetic [PDF]
, 2007 Trifluoroethanol has been elaborated, via a telescoped sequence involving a metalated difluoroenol, a difluoroallylic alcohol, [2,3]-Wittig rearrangement, and ultimately an RCM reaction and requiring minimal intermediate purification, to a number of ...
Miles, Jonathan A. L. +4 more
core +1 more source
Arthritis &Rheumatology, Accepted Article.Background Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes and decreased nephrin production.
Rhea Bhargava +9 more
wiley +1 more source
Diversification of Glycosyl Compounds via Glycosyl Radicals
Angewandte Chemie, 2023 AbstractGlycosyl radical functionalization is one of the central topics in synthetic carbohydrate chemistry. Recent advances in metal‐catalyzed cross‐coupling chemistry and metallaphotoredox catalysis provided powerful platforms for glycosyl radical diversification.
Yi Jiang +3 more
openaire +2 more sources
Genetic Locus and Structural Characterization of the Biochemical Defect in the O-Antigenic Polysaccharide of the Symbiotically Deficient \u3cem\u3eRhizobium etli\u3c/em\u3e Mutant, CE166 [PDF]
, 2003 The O-antigen polysaccharide (OPS) of Rhizobium etli CE3 lipopolysaccharide (LPS) is linked to the core oligosaccharide via an N-acetylquinovosaminosyl (QuiNAc) residue.
Box, Jodie M. +3 more
core +1 more source
XTHs from Fragaria vesca: Genomic structure and transcriptomic analysis in ripening fruit and other tissues [PDF]
, 2017 Indexación: Scopus.Background: Fragaria vesca or 'woodland strawberry' has emerged as an attractive model for the study of ripening of non-climacteric fruit. It has several advantages, such as its small genome and its diploidy. The recent availability of
Davis, T.M. +5 more
core +5 more sources
Advances in Metal‐Free Transamidation: A Sustainable Approach to Amide Bond Formation
Chemistry – An Asian Journal, EarlyView.This review highlights the recent developments of transamidation reactions under metal‐free reaction conditions. Various amines including weak nucleophilic amines such as aromatic amines have been used to achieve the transamidation reactions under mild and relatively green reaction conditions. Abstract The amide functionalities are a crucial functional
Niharan Sivaraj +2 more
wiley +1 more source