Results 151 to 160 of about 5,898,960 (197)

Bioactive microbial metabolites from glycyrrhetinic acid

Phytochemistry, 2010
Biotransformation of 18beta-glycyrrhetinic acid, using Absidia pseudocylinderospora ATCC 24169, Gliocladium viride ATCC 10097 and Cunninghamella echinulata ATCC 8688a afforded seven metabolites, which were identified by different spectroscopic techniques (1H, 13C NMR, DEPT, 1H-1H COSY, HMBC and HMQC). Three of these metabolites, viz.
Maatooq, Galal T., Marzouk, Amani M., Gray, A.I., Rosazza, John P.   +3 more
openaire   +3 more sources

Formulation of pH-responsive lipid-polymer hybrid nanoparticles for co-delivery and enhancement of the antibacterial activity of vancomycin and 18β-glycyrrhetinic acid

, 2021
Despite advancement in the control and therapeutics of infectious diseases, antimicrobial resistance remains a global burden. Hence there is a need for novel strategies that improve and potentiate available antibiotics to prevent a regress to a pre ...
Yajna Jaglal, Nawras Osman, Calvin A. Omolo, Chunderika. Mocktar, Nikita Devnarain, T. Govender   +5 more
semanticscholar   +1 more source

Metabolism of Glycyrrhetinic Acid in Human Subjects

Nature, 1954
IN a series of publications Groen, Pelser, Frenkel, Kamminga and Willebrands1–6 have reported on the successful treatment of Addison's disease by extract of liquorice, glycyrrhizinic acid or glycyrrhetinic acid. It was shown that either the crude liquorice extract or its active component produced an effect on electrolyte metabolism which was entirely ...
V M, VAN KATWIJK, L G, HUIS IN'T VELD
openaire   +2 more sources

Selective inhibition of 11β-hydroxysteroid dehydrogenase 1 by 18α-glycyrrhetinic acid but not 18β-glycyrrhetinic acid

The Journal of Steroid Biochemistry and Molecular Biology, 2009
Elevated cortisol concentrations have been associated with metabolic diseases such as diabetes type 2 and obesity. 11beta-hydroxysteroid dehydrogenase (11beta-HSD) type 1, catalyzing the conversion of inactive 11-ketoglucocorticoids into their active 11beta-hydroxy forms, plays an important role in the regulation of cortisol levels within specific ...
Classen-Houben, D., Schuster, D., Da Cunha, T., Odermatt, A., Wolber, G., Jordis, U., Kueenburg, B.   +6 more
openaire   +2 more sources

Glycyrrhetinic acid induces oxidative/nitrative stress and drives ferroptosis through activating NADPH oxidases and iNOS, and depriving glutathione in triple-negative breast cancer cells.

Free Radical Biology & Medicine, 2021
Y-Q Wen, Hansen Chen, Lu Zhang, Meiling Wu, Feng Zhang, Dan Yang, Jiangang Shen, Jianping Chen   +7 more
semanticscholar   +1 more source

Prolonged Administration of Glycyrrhetinic Acid in Rats

Journal of Pharmaceutical Sciences, 1964
Prolonged administration of glycyrrhetinic acid was studied in immature female rats, castrated male donor parabionts, and mature cyclic rats. Glycyrrhetinic acid treatment for 7 days interfered with the uterotrophic response of immature rats to estradiol benzoate but had no effect on the pituitary-ACTH content.
openaire   +2 more sources

Neuroprotective effects of 18β-glycyrrhetinic acid against bisphenol A-induced neurotoxicity in rats: involvement of neuronal apoptosis, endoplasmic reticulum stress and JAK1/STAT1 signaling pathway

Metabolic brain disease, 2022
Cuneyt Caglayan, F. Kandemir, A. Ayna, C. Gür, S. Küçükler, E. Darendelioğlu   +5 more
semanticscholar   +1 more source

Glycyrrhetinic Acid

BMJ, 1960
E. E. Turner, R. T. Williams
openaire   +2 more sources

Protective Effects of 18β-Glycyrrhetinic Acid on Neonatal Rats with Hyperoxia Exposure

Inflammation, 2022
Cai Qing, Liu Ziyun, Xuefei Yu, Zhao Xinyi, Xindong Xue, Jianhua Fu   +5 more
semanticscholar   +1 more source

Glycyrrhetinic Acid

2018
Wen Zhang, Qi-Meng Zhou, Guan-Hua Du
openaire   +1 more source